The Music Of Life

Author: Denis Noble
Publisher: OUP Oxford
ISBN: 9780191578809
Size: 46.54 MB
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What is Life? Decades of research have resulted in the full mapping of the human genome - three billion pairs of code whose functions are only now being understood. The gene's eye view of life, advocated by evolutionary biology, sees living bodies as mere vehicles for the replication of the genetic codes. But for a physiologist, working with the living organism, the view is a very different one. Denis Noble is a world renowned physiologist, and sets out an alternative view to the question - one that becomes deeply significant in terms of the living, breathing organism. The genome is not life itself. Noble argues that far from genes building organisms, they should be seen as prisoners of the organism. The view of life presented in this little, modern, post-genome project reflection on the nature of life, is that of the systems biologist: to understand what life is, we must view it at a variety of different levels, all interacting with each other in a complex web. It is that emergent web, full of feedback between levels, from the gene to the wider environment, that is life. It is a kind of music. Including stories from Noble's own research experience, his work on the heartbeat, musical metaphors, and elements of linguistics and Chinese culture, this very personal and at times deeply lyrical book sets out the systems biology view of life.

The Music Of Life

Author: Denis Noble
Publisher: Oxford University Press
ISBN: 0199228361
Size: 58.69 MB
Format: PDF, ePub, Docs
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What is Life? Decades of research have resulted in the full mapping of the human genome - three billion pairs of code whose functions are only now being understood. The gene's eye view of life, advocated by evolutionary biology, sees living bodies as mere vehicles for the replication of the genetic codes.But for a physiologist, working with the living organism, the view is a very different one. Denis Noble is a world renowned physiologist, and sets out an alternative view to the question - one that becomes deeply significant in terms of the living, breathing organism. The genome is not life itself. Noble argues that far from genes building organisms, they should be seen as prisoners of the organism.The view of life presented in this little, modern, post-genome project reflection on the nature of life, is that of the systems biologist: to understand what life is, we must view it at a variety of different levels, all interacting with each other in a complex web. It is that emergent web, full of feedback between levels, from the gene to the wider environment, that is life. It is a kind of music.Including stories from Noble's own research experience, his work on the heartbeat, musical metaphors, and elements of linguistics and Chinese culture, this very personal and at times deeply lyrical book sets out thesystems biology view of life.

The Music Of Life

Author: Denis Noble
Publisher: Oxford University Press on Demand
ISBN: 0199295735
Size: 71.31 MB
Format: PDF, ePub, Docs
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What is life? The gene's eye view of life sees living bodies as mere vehicles for the replication of genetic codes. Noble sets out an alternative view - that the genome is not life itself, and argues that genes should be seen as prisoners of the organism. To understand what life is, we must view it at a variety of different levels, all interacting with each other in a complex web, full of feedback between levels, from the gene to the wider environment. It is that web, a kind of music, that is life. Including stories from Noble's own research experience, this personal and at times lyrical book sets out the systems biology view of life.

Evolution

Author: James Alan Shapiro
Publisher: Pearson Education
ISBN: 0132780933
Size: 70.12 MB
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James A. Shapiro proposes an important new paradigm for understanding biological evolution, the core organizing principle of biology. Shapiro introduces crucial new molecular evidence that tests the conventional scientific view of evolution based on the neo-Darwinian synthesis, shows why this view is inadequate to today's evidence, and presents a compelling alternative view of the evolutionary process that reflects the shift in life sciences towards a more information- and systems-based approach in Evolution: A View from the 21st Century. Shapiro integrates advances in symbiogenesis, epigenetics, and saltationism into a unified approach that views evolutionary change as an active cell process, regulated epigenetically and capable of making rapid large changes by horizontal DNA transfer, inter-specific hybridization, whole genome doubling, symbiogenesis, or massive genome restructuring. Evolution marshals extensive evidence in support of a fundamental reinterpretation of evolutionary processes, including more than 1,100 references to the scientific literature. Shapiro's work will generate extensive discussion throughout the biological community, and may significantly change your own thinking about how life has evolved. It also has major implications for evolutionary computation, information science, and the growing synthesis of the physical and biological sciences.

Life Explained

Author: Michel Morange
Publisher: Yale University Press
ISBN: 0300142390
Size: 10.51 MB
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Fifty years ago Francis Crick and James D. Watson proposed the double helix model for the DNA molecule. They believed they had, as Crick put it, discovered the secret of life, and many agreed. But in the intervening years, science has marched sometimes leaped forward, and now the question What is life? must be posed once again.In this accessible and fascinating book, Michel Morange draws on recent advances in molecular genetics, evolutionary biology, astrobiology, and other disciplines to find today s answers to the question of life. He begins by discussing the various answers that have been formulated in the past, setting contemporary definitions of life within a rich philosophical and scientific tradition that reaches back to ancient Greece. Then, with impeccable logic and a wealth of appropriate detail, Morange proceeds to lay out the fundamental characteristics that define life. The road to an understanding of life remains incompletely charted, he concludes, but the nature of its final destination is no longer an enigma."

The Logic Of Life

Author: C. A. R. Boyd
Publisher: Oxford University Press, USA
ISBN: 9780192624178
Size: 57.31 MB
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A highly challenging collection of essays by eminent scientists on the theme of integrative approaches to physiological questions, this book discusses the changing boundaries between different disciplines in modern experimental biology. The contributors are experts in the fields of integrative physiology, cellular evolution, control mechanisms, endocrinology, and behavioral biology. Conceived as a tribute to the 1993 International Congress of Physiological Sciences, this important work matches the immense challenge of modern biological science at the end of the twentieth century.

What S In Your Genes

Author: Katie McKissick
Publisher: Simon and Schuster
ISBN: 1440567654
Size: 21.97 MB
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A crash course in genetics! Everyone knows that if you come from a family of brunettes, you're likely to be born with brown hair. But did you know your hair color may also affect how often you get sunburned? Or how often you need to take vitamin supplements? What's in Your Genes? goes beyond Gregor Mendel and dominant/recessive genes to show you all the ins and outs of what determines your DNA. Each entry provides you with a sneak peek into your DNA sequence and teaches you exactly how your body is able to create that wonderful you-ness that no one else has. From your tastebuds to your eye color to your obsession with clinical-strength deodorants, this book not only guides you through the history and study of genetics, but also shows you how those four little letters in your DNA make you who you are. Complete with imaginative illustrations, What's in Your Genes? reveals all there is to know about heredity--like the science behind vibrant red hair, perfect teeth, and your ability to see in color.

Making Sense Of Genes

Author: Kostas Kampourakis
Publisher: Cambridge University Press
ISBN: 1107128137
Size: 10.69 MB
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An accessible but rigorous introduction to genes for non-experts, explaining what genes are and what they can and cannot do.

Lifelines

Author: Steven Rose
Publisher: Oxford University Press
ISBN: 9780198034247
Size: 52.61 MB
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A distinct voice in the nature/nurture debate, Rose's series of essays are a response to the biological reductionism of Richard Dawkins's book, The Selfish Gene (OUP, 1990), which insists that all aspects of human life are in our genes, and everything arises as a consequence of natural selection. Rose argues that life depends on the elaborate web of interactions that occur within cells, organisms, and ecosystems, and in which DNA has but one part to play.