The Chemistry And Biology Of Nitroxyl Hno

Author: Fabio Doctorovich
Publisher: Elsevier
ISBN: 0128011645
Size: 29.43 MB
Format: PDF
View: 4072
Download
The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of areas of chemistry (inorganic, organic, organometallic, biochemistry, physical, and analytical); biology (molecular, cellular, physiological, and enzymology); pharmacy; and medicine. This book begins by exploring the unique molecule’s structure and reactivity, including important reactions with small molecules, thiols, porphyrins, and key proteins, before discussing chemical and biological sources of nitroxyl. Advanced chapters discuss methods for both trapping and detecting nitroxyl by spectroscopy, electrochemistry, and fluorescent inorganic cellular probing. Expanding on the compound’s foundational chemistry, this book then explores its molecular physiology to offer insight into its biological implications, pharmacological effects, and practical issues. Presents the first book on HNO (nitroxyl or azanone), an increasingly important molecule in biochemistry and pharmaceutical research Provides a valuable coverage of HNO’s chemical structure and significant reactions, including practical guidance on working with this highly reactive molecule Contains high quality content from recognized experts in both industry and academia

Nitrosation Reactions And The Chemistry Of Nitric Oxide

Author: D.L.H. Williams
Publisher: Elsevier
ISBN: 9780080473604
Size: 75.44 MB
Format: PDF
View: 1017
Download
Since 1988, there has been much literature published on the chemistry of nitric oxide, particularly in the field of S-nitrosation and the chemistry of S-nitroso compounds. Written by a chemist for the chemistry community, this book provides an update of the chemistry of nitrosation reactions, dealing with both the synthetic and mechanistic aspects of these reactions. It also looks at the chemistry of nitric oxide in relation to the amazing biological properties of this simple diatomic molecule, which were unknown until around 1990. * Provides an update on previously published literature on nitric oxide chemistry * Contains chapters on reagents for nitrosation, nitrosation at nitrogen, aliphatic and aromatic carbon, oxygen, sulfur and metal centres * Looks at hot research topics such as synthesis, properties and reactions of s-nitrosothiols

Nitric Oxide

Author: Louis J. Ignarro
Publisher: Academic Press
ISBN: 0128043199
Size: 42.88 MB
Format: PDF, Mobi
View: 5705
Download
Nitric Oxide: Biology and Pathobiology, Third Edition, provides information on nitric oxide, a signaling molecule of key importance for the cardiovascular system that regulates blood pressure and blood flow to different organs. With recent links to the role of nitric oxide in the expression of healthy benefits of controlled diet and aerobic exercise, and the reactions of nitric oxide that can impact cell signaling, this book provides a comprehensive resource during a time when increased research attention is being paid across the fields of biochemistry, chemistry, molecular biology, gene therapy, cell biology, immunology, pharmacology, neuroscience, and physiology. Includes perspectives from Jack Lancaster on the discovery of EDRF and nitric oxide Provides detailed coverage of the new gaseous signaling agents Features expanded coverage on the principles of biology, including nitric oxide synthases, nitrite and nitrate biology and pathobiology, and signaling mechanisms Incorporates expanded pathobiology coverage, including nitric oxide and cardiovascular function, obesity, diabetes, and erectile function/dysfunction

Gasotransmitters In Plants

Author: Lorenzo Lamattina
Publisher: Springer
ISBN: 3319407139
Size: 27.88 MB
Format: PDF, ePub, Docs
View: 5633
Download
This book describes the three gasotransmitters nitric oxide (NO), hydrogen sulphide (H2S) and carbon monoxide (CO) and their function as intracellular signalling molecules in plants. Common properties are shared by NO, H2S and CO: they are beneficial at low concentrations but hazardous in higher amounts; they are small molecules of gas; they can freely cross cell membranes; their effects do not rely on receptors; they are generated enzymatically and their production is regulated; their functions can be mimicked by exogenous application; and their cellular effects may or may not be mediated by second messengers, but have specific cellular and molecular targets. In plants, many aspects of the biology of gasotransmitters remain completely unknown and generate intriguing questions, which will be discussed in this book.

Nitric Oxide In Plants Metabolism And Role In Stress Physiology

Author: M. Nasir Khan
Publisher: Springer
ISBN: 3319067109
Size: 11.10 MB
Format: PDF, Mobi
View: 3383
Download
This book covers the key features of nitric oxide (NO) in plants. Comprising nine chapters, Part I highlights its metabolism and identification in plants. Part II, which consists of eight chapters, focuses on the chemical, physical and biochemical properties of the NO molecule and its derivatives; on its functional role and mode of action; and on its signaling and interaction with phytohormones, mineral nutrients, biomolecules, ions and ion channels in plants under abiotic stresses. Combining the expertise of leading researchers in the field, the book provides a concise overview of plant NO biology and offers a valuable reference work.

Exploring Canework In Polymer Clay

Author: Patricia Kimle
Publisher: Kalmbach Books
ISBN: 0871167751
Size: 56.70 MB
Format: PDF, Kindle
View: 6965
Download
Exploring Canework in Polymer Clay: Color, Pattern and Surface Design gives jewelry makers in-depth instruction in polymer clay cane making. Beginning with polymer clay basics and color theory for pleasing combinations in canework, the book also provides detailed lessons in constructing, reducing, and repeating patterns in canes as well as how to use canes to create repeating patterns for larger surface design. The book teaches eight unique cane styles, and a variety of ways to incorporate cane patterns into sophisticated finished jewelry. Techniques include striped, checkerboard, spiral, bull’s eye, kaleidoscope, floral, combination, and translucent overlay canes. Detailed step-by-step instructions and clear process photography for each cane styleguide readers of any skill level. Lessons are followed by vibrant jewelry -- necklaces, earrings, bracelets, pendants, or brooches -- incorporating the pattern just taught. A stunning and inspirational gallery of finished jewelry, all designed by award-winning author Patricia Kimle, completes this beautiful book.

Synthetic Biology Handbook

Author: Darren N. Nesbeth
Publisher: CRC Press
ISBN: 1466568488
Size: 52.66 MB
Format: PDF, ePub
View: 5148
Download
The Synthetic Biology Handbook explains the major goals of the field of synthetic biology and presents the technical details of the latest advances made in achieving those goals. Offering a comprehensive overview of the current areas of focus in synthetic biology, this handbook: Explores the standardisation of classic molecular bioscience approaches Addresses the societal context and potential impacts of synthetic biology Discusses the use of legacy systems as tools for new product development Examines the design and construction of de novo cells and genetic codes Describes computational methods for designing genes and gene networks Thus, the Synthetic Biology Handbook provides an accurate sense of the scope of synthetic biology today. The handbook also affords readers with an opportunity to scrutinize the underlying science and decide for themselves what aspects of synthetic biology are most valuable to their research and practice.

Heterocyclic Chemistry At A Glance

Author: John A. Joule
Publisher: John Wiley & Sons
ISBN: 1118380193
Size: 16.54 MB
Format: PDF, ePub
View: 1858
Download
Heterocyclic chemistry is a central part of organic chemistry and biochemistry, dealing with a particular set of chemical structures; organic compounds with a ring structure containing at least one heteroatom (commonly nitrogen, oxygen or sulfur). Heterocyclic Chemistry at a Glance, Second Edition provides both an introduction and summary of the main principles and reactions of heterocyclic chemistry, for students studying chemistry and related courses at undergraduate level. This second edition has been much expanded, allowing for a more thorough treatment of key principles and the inclusion of extra examples and illustrations, including heterocycles used in electronics, explosives, polymers, dyestuffs, pigments and that occur in food. All chapters have been revised and updated, including references to books and reviews, and student exercises, with answers on line at http://booksupport.wiley.com. New to this edition is the use of colour in schemes and diagrams highlighting parts of products (or intermediates) where a change in structure or bonding has taken place. Based on the highly successful and student-friendly “at a glance” approach, the material developed in this book has been chosen to help the student grasp the essence of heterocyclic chemistry, ensuring that they can confidently use that knowledge when required. The structure of the book allows for quick assimilation, understanding and recall of key concepts, facts and definitions, providing an invaluable aid to revision for students preparing for examinations. Reviews for the first edition: “This book can be recommended to students looking for a textbook on heterocyclic chemistry. The organization of the material is oriented towards the needs of undergraduate students, but nevertheless the book is comprehensive and will also be of value for more advanced readers." Heterocycles "Joule and Mills have succeeded here in condensing the essence of introductory undergraduate heterocyclic chemistry into a slim volume, presented (as is the way in this series) in an A4 page format and in a very easy-to-grasp style with many structures and reactions. All of the key areas are covered.” Chemistry World