Statistical Models In Epidemiology The Environment And Clinical Trials

Author: M.Elizabeth Halloran
Publisher: Springer Science & Business Media
ISBN: 1461212847
Size: 44.51 MB
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This IMA Volume in Mathematics and its Applications STATISTICAL MODELS IN EPIDEMIOLOGY, THE ENVIRONMENT,AND CLINICAL TRIALS is a combined proceedings on "Design and Analysis of Clinical Trials" and "Statistics and Epidemiology: Environment and Health. " This volume is the third series based on the proceedings of a very successful 1997 IMA Summer Program on "Statistics in the Health Sciences. " I would like to thank the organizers: M. Elizabeth Halloran of Emory University (Biostatistics) and Donald A. Berry of Duke University (Insti tute of Statistics and Decision Sciences and Cancer Center Biostatistics) for their excellent work as organizers of the meeting and for editing the proceedings. I am grateful to Seymour Geisser of University of Minnesota (Statistics), Patricia Grambsch, University of Minnesota (Biostatistics); Joel Greenhouse, Carnegie Mellon University (Statistics); Nicholas Lange, Harvard Medical School (Brain Imaging Center, McLean Hospital); Barry Margolin, University of North Carolina-Chapel Hill (Biostatistics); Sandy Weisberg, University of Minnesota (Statistics); Scott Zeger, Johns Hop kins University (Biostatistics); and Marvin Zelen, Harvard School of Public Health (Biostatistics) for organizing the six weeks summer program. I also take this opportunity to thank the National Science Foundation (NSF) and the Army Research Office (ARO), whose financial support made the workshop possible. Willard Miller, Jr.

Integrating Clinical Research Into Epidemic Response

Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309457769
Size: 36.67 MB
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The 2014â€"2015 Ebola epidemic in western Africa was the longest and most deadly Ebola epidemic in history, resulting in 28,616 cases and 11,310 deaths in Guinea, Liberia, and Sierra Leone. The Ebola virus has been known since 1976, when two separate outbreaks were identified in the Democratic Republic of Congo (then Zaire) and South Sudan (then Sudan). However, because all Ebola outbreaks prior to that in West Africa in 2014â€"2015 were relatively isolated and of short duration, little was known about how to best manage patients to improve survival, and there were no approved therapeutics or vaccines. When the World Heath Organization declared the 2014-2015 epidemic a public health emergency of international concern in August 2014, several teams began conducting formal clinical trials in the Ebola affected countries during the outbreak. Integrating Clinical Research into Epidemic Response: The Ebola Experience assesses the value of the clinical trials held during the 2014â€"2015 epidemic and makes recommendations about how the conduct of trials could be improved in the context of a future international emerging or re-emerging infectious disease events.

Epidemiology And Biostatistics

Author: Bryan Kestenbaum
Publisher: Springer Science & Business Media
ISBN: 9780387884332
Size: 21.63 MB
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Concise, fast-paced, intensive introduction to clinical research design for students and clinical research professionals Readers will gain sufficient knowledge to pass the United States Medical Licensing Examination part I section in Epidemiology

Clinical Research Informatics

Author: Rachel Richesson
Publisher: Springer Science & Business Media
ISBN: 1848824475
Size: 17.12 MB
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The purpose of the book is to provide an overview of clinical research (types), activities, and areas where informatics and IT could fit into various activities and business practices. This book will introduce and apply informatics concepts only as they have particular relevance to clinical research settings.

Statistical Models In Epidemiology

Author: David Clayton
Publisher: Oxford University Press
ISBN: 0199671184
Size: 67.32 MB
Format: PDF
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This self-contained account of the statistical basis of epidemiology has been written for those with a basic training in biology. No previous knowledge of the subject is assumed and mathematics is deliberately kept at a manageable level. Based on a highly successful course, this book explains the essential statistics for all epidemiologists.

Common Errors In Statistics And How To Avoid Them

Author: Phillip I. Good
Publisher: John Wiley & Sons
ISBN: 1118360117
Size: 13.81 MB
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Praise for Common Errors in Statistics (and How to Avoid Them) "A very engaging and valuable book for all who use statistics in any setting." —CHOICE "Addresses popular mistakes often made in data collection and provides an indispensable guide to accurate statistical analysis and reporting. The authors' emphasis on careful practice, combined with a focus on the development of solutions, reveals the true value of statistics when applied correctly in any area of research." —MAA Reviews Common Errors in Statistics (and How to Avoid Them), Fourth Edition provides a mathematically rigorous, yet readily accessible foundation in statistics for experienced readers as well as students learning to design and complete experiments, surveys, and clinical trials. Providing a consistent level of coherency throughout, the highly readable Fourth Edition focuses on debunking popular myths, analyzing common mistakes, and instructing readers on how to choose the appropriate statistical technique to address their specific task. The authors begin with an introduction to the main sources of error and provide techniques for avoiding them. Subsequent chapters outline key methods and practices for accurate analysis, reporting, and model building. The Fourth Edition features newly added topics, including: Baseline data Detecting fraud Linear regression versus linear behavior Case control studies Minimum reporting requirements Non-random samples The book concludes with a glossary that outlines key terms, and an extensive bibliography with several hundred citations directing readers to resources for further study. Presented in an easy-to-follow style, Common Errors in Statistics, Fourth Edition is an excellent book for students and professionals in industry, government, medicine, and the social sciences.

Exposure Science In The 21st Century

Author: Committee on Human and Environmental Exposure Science in the 21st Century
Publisher: National Academies Press
ISBN: 0309264685
Size: 21.75 MB
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From the use of personal products to our consumption of food, water, and air, people are exposed to a wide array of agents each day--many with the potential to affect health. Exposure Science in the 21st Century: A Vision and A Strategy investigates the contact of humans or other organisms with those agents (that is, chemical, physical, and biologic stressors) and their fate in living systems. The concept of exposure science has been instrumental in helping us understand how stressors affect human and ecosystem health, and in efforts to prevent or reduce contact with harmful stressors. In this way exposure science has played an integral role in many areas of environmental health, and can help meet growing needs in environmental regulation, urban and ecosystem planning, and disaster management. Exposure Science in the 21st Century: A Vision and A Strategy explains that there are increasing demands for exposure science information, for example to meet needs for data on the thousands of chemicals introduced into the market each year, and to better understand the health effects of prolonged low-level exposure to stressors. Recent advances in tools and technologies--including sensor systems, analytic methods, molecular technologies, computational tools, and bioinformatics--have provided the potential for more accurate and comprehensive exposure science data than ever before. This report also provides a roadmap to take advantage of the technologic innovations and strategic collaborations to move exposure science into the future.

Water Quality

Author: Fewtrel L.
Publisher: World Health Organization
ISBN: 924154533X
Size: 72.83 MB
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The quality of water, whether it is used for drinking, irrigation or recreational purposes, is significant for health in both developing and developed countries worldwide. This book is based on a programme of work undertaken by an international group of experts during 1999-2001. The aim was to develop a harmonised framework of effective and affordable guidelines and standards to improve the risk assessment and management of water-related microbial hazards. This book will be useful to all those concerned with issues relating to microbial water quality and health, including environmental and public health scientists, water scientists, policy makers and those responsible for developing standards and regulations.

Facilitating Interdisciplinary Research

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 9780309165488
Size: 45.92 MB
Format: PDF
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Facilitating Interdisciplinary Research examines current interdisciplinary research efforts and recommends ways to stimulate and support such research. Advances in science and engineering increasingly require the collaboration of scholars from various fields. This shift is driven by the need to address complex problems that cut across traditional disciplines, and the capacity of new technologies to both transform existing disciplines and generate new ones. At the same time, however, interdisciplinary research can be impeded by policies on hiring, promotion, tenure, proposal review, and resource allocation that favor traditional disciplines. This report identifies steps that researchers, teachers, students, institutions, funding organizations, and disciplinary societies can take to more effectively conduct, facilitate, and evaluate interdisciplinary research programs and projects. Throughout the report key concepts are illustrated with case studies and results of the committee’s surveys of individual researchers and university provosts.