Science Business

Author: Gary P. Pisano
Publisher: Harvard Business Press
ISBN: 9781591398400
Size: 53.12 MB
Format: PDF
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Why has the biotechnology industry failed to perform up to expectations? This book attempts to answer this question by providing a critique of the industry. It reveals the causes of biotech's problems and offers an analysis on how the industry works. It also provides prescriptions for companies, seeking ways to improve the industry's performance.

Science Lessons

Author: Gordon M. Binder
Publisher: Harvard Business School Press
ISBN:
Size: 26.25 MB
Format: PDF, Mobi
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The start of a start-up - Amgen goes public - The business of science meets the science of business - From IPO to EPO in four months - EPO on trial - Partnerships made in heaven and that other place - Red hot summer - Nuclear winter - How to build a winning team - How Amgen kept employees committed - The value of ethics in business - My failed retirement.

Biotechnology Entrepreneurship

Author: Craig Shimasaki
Publisher: Academic Press
ISBN: 0124047475
Size: 61.34 MB
Format: PDF, Docs
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As an authoritative guide to biotechnology enterprise and entrepreneurship, Biotechnology Entrepreneurship and Management supports the international community in training the biotechnology leaders of tomorrow. Outlining fundamental concepts vital to graduate students and practitioners entering the biotech industry in management or in any entrepreneurial capacity, Biotechnology Entrepreneurship and Management provides tested strategies and hard-won lessons from a leading board of educators and practitioners. It provides a ‘how-to’ for individuals training at any level for the biotech industry, from macro to micro. Coverage ranges from the initial challenge of translating a technology idea into a working business case, through securing angel investment, and in managing all aspects of the result: business valuation, business development, partnering, biological manufacturing, FDA approvals and regulatory requirements. An engaging and user-friendly style is complemented by diverse diagrams, graphics and business flow charts with decision trees to support effective management and decision making. Provides tested strategies and lessons in an engaging and user-friendly style supplemented by tailored pedagogy, training tips and overview sidebars Case studies are interspersed throughout each chapter to support key concepts and best practices. Enhanced by use of numerous detailed graphics, tables and flow charts

Preserving The Promise

Author: Scott Dessain
Publisher: Academic Press
ISBN: 0128092092
Size: 25.11 MB
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Preserving the Promise: Improving the Culture of Biotech Investment critically examines why most biotech startups fail, as they emerge from universities into an ecosystem that inhibits rather than encourages innovation. This "Valley of Death" squanders our public investments in medical research and with them, the promise of longer and healthier lives. The authors explicate the Translation Gap faced by early stage biotech companies, the result of problematic technology transfer and investment practices, and provide specific prescriptions for improving translation of important discoveries into safe and effective therapies. In Preserving the Promise, Dessain and Fishman build on their collective experience as company founders, healthcare investor (Fishman) and physician/scientist (Dessain). The book offers a forward-looking, critical analysis of "conventional wisdom" that encumbers commercialization practices. It exposes the self-defeating habits of drug development in the Valley of Death, that waste money and extinguish innovative technologies through distorted financial incentives. Explains why translation of biotech discovery into medicine succeeds so infrequently that it’s been dubbed the Valley of Death Uncovers specific decision-making strategies that more effectively align incentives, improving clinical and financial outcomes for investors, inventor/entrepreneurs, and patients Examines the critical, early stages of commercialization, where technology transfer offices and Angels act as gatekeepers to development, and where tension between short-term financial and long-term clinical aspirations sinks important technologies Deconstructs the forces driving biotech, recasts them in a proven conceptual framework, and offers practical guidance for making the system better

Producing Prosperity

Author: Gary P. Pisano
Publisher: Harvard Business Press
ISBN: 1422187543
Size: 26.68 MB
Format: PDF, ePub
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Manufacturing’s central role in global innovation Companies compete on the decisions they make. For years—even decades—in response to intensifying global competition, companies decided to outsource their manufacturing operations in order to reduce costs. But we are now seeing the alarming long-term effect of those choices: in many cases, once manufacturing capabilities go away, so does much of the ability to innovate and compete. Manufacturing, it turns out, really matters in an innovation-driven economy. In Producing Prosperity, Harvard Business School professors Gary Pisano and Willy Shih show the disastrous consequences of years of poor sourcing decisions and underinvestment in manufacturing capabilities. They reveal how today’s undervalued manufacturing operations often hold the seeds of tomorrow’s innovative new products, arguing that companies must reinvest in new product and process development in the US industrial sector. Only by reviving this “industrial commons” can the world’s largest economy build the expertise and manufacturing muscle to regain competitive advantage. America needs a manufacturing renaissance—for restoring itself, and for the global economy as a whole. This will require major changes. Pisano and Shih show how company-level choices are key to the sustained success of industries and economies, and they provide business leaders with a framework for understanding the links between manufacturing and innovation that will enable them to make better outsourcing decisions. They also detail how government must change its support of basic and applied scientific research, and promote collaboration between business and academia. For executives, policymakers, academics, and innovators alike, Producing Prosperity provides the clearest and most compelling account yet of how the American economy lost its competitive edge—and how to get it back.

Beyond Biotechnology

Author: Craig Holdrege
Publisher: University Press of Kentucky
ISBN: 0813129478
Size: 57.75 MB
Format: PDF, Docs
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In 2001 the Human Genome Project announced that it had successfully mapped the entire genetic content of human DNA. Scientists, politicians, theologians, and pundits speculated about what would follow, conjuring everything from nightmare scenarios of state-controlled eugenics to the hope of engineering disease-resistant newborns. As with debates surrounding stem-cell research, the seemingly endless possibilities of genetic engineering will continue to influence public opinion and policy into the foreseeable future. Beyond Biotechnology: The Barren Promise of Genetic Engineering distinguishes between the hype and reality of this technology and explains the nuanced and delicate relationship between science and nature. Authors Craig Holdrege and Steve Talbott evaluate the current state of genetic science and examine its potential applications, particularly in agriculture and medicine, as well as the possible dangers. The authors show how the popular view of genetics does not include an understanding of the ways in which genes actually work together in organisms. Simplistic and reductionist views of genes lead to unrealistic expectations and, ultimately, disappointment in the results that genetic engineering actually delivers. The authors explore new developments in genetics, from the discovery of “non-Darwinian” adaptative mutations in bacteria to evidence that suggests that organisms are far more than mere collections of genetically driven mechanisms. While examining these issues, the authors also answer vital questions that get to the essence of genetic interaction with human biology: Does DNA “manage” an organism any more than the organism manages its DNA? Should genetically engineered products be labeled as such? Do the methods of the genetic engineer resemble the centuries-old practices of animal husbandry? Written for lay readers, Beyond Biotechnology is an accessible introduction to the complicated issues of genetic engineering and its potential applications. In the unexplored space between nature and laboratory, a new science is waiting to emerge. Technology-based social and environmental solutions will remain tenuous and at risk of reversal as long as our culture is alienated from the plants and animals on which all life depends.

Biology Is Technology

Author: Robert H. Carlson
Publisher: Harvard University Press
ISBN: 0674053621
Size: 67.76 MB
Format: PDF, ePub, Mobi
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In Biology Is Technology, author Robert Carlson offers a uniquely informed perspective on the endeavors that contribute to current progress in the science of biological systems and the technology used to manipulate them.

Frankenstein S Cat

Author: Emily Anthes
Publisher: Oneworld Publications
ISBN: 1780742169
Size: 32.36 MB
Format: PDF
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From the petri dish to the pet shop, meet the high-tech menagerie of the near future, as humans reinvent the animal kingdom Fluorescent fish that glow near pollution. Dolphins with prosthetic fins. Robot-armoured beetles that military handlers can send on spy missions. Beloved pet pigs resurrected from DNA. Scientists have already begun to create these high-tech hybrids to serve human whims and needs. What if a cow could be engineered to no longer feel pain – should we design a herd that would assuage our guilt over eating meat? Acclaimed science writer Emily Anthes travels round the globe to meet the fauna of the future, from the Scottish birthplace of Dolly the sheep and other clones to a ‘pharm’ for cancer-fighting chickens. Frankenstein’s Cat is an eye-opening exploration of weird science – and how we are playing god in the animal world.

Radical Evolution

Author: Joel Garreau
Publisher: Random House Digital, Inc.
ISBN: 0767915038
Size: 50.67 MB
Format: PDF
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Arguing that the acceleration of technological innovation is setting the course for the next stage of human evolution, the author of Edge City raises thought-provoking questions about human culture, society, and the very nature of humankind. Reprint. 15,000 first printing.