Population Genetics

Author: John H. Gillespie
Publisher: JHU Press
ISBN: 9781421401706
Size: 60.68 MB
Format: PDF
View: 422
Download
This book is indispensable for students working in a laboratory setting or studying free-ranging populations.

Population Genetics

Author: John H. Gillespie
Publisher: JHU Press
ISBN: 0801880084
Size: 29.86 MB
Format: PDF
View: 3018
Download
This concise introduction addresses the theories behind population genetics and relevant empirical evidence, genetic drift, natural selection, nonrandom mating, quantitative genetics, and the evolutionary advantage of sex.

Population Genetics

Author: Matthew Hamilton
Publisher: John Wiley & Sons
ISBN: 1444362453
Size: 32.29 MB
Format: PDF
View: 5291
Download
This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates. Pedagogical features in the text include: Interact boxes that guide readers step-by-step through computer simulations using public domain software. Math boxes that fully explain mathematical derivations. Methods boxes that give insight into the use of actual genetic data. Numerous Problem boxes are integrated into the text to reinforce concepts as they are encountered. Dedicated website at www.wiley.com/go/hamiltongenetics This text also offers a highly accessible introduction to coalescent theory, the major conceptual advance in population genetics of the last two decades.

Population Genetics And Microevolutionary Theory

Author: Alan R. Templeton
Publisher: John Wiley & Sons
ISBN: 0470047216
Size: 79.46 MB
Format: PDF, Docs
View: 4995
Download
The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links

The Causes Of Molecular Evolution

Author: John H. Gillespie
Publisher: Oxford University Press on Demand
ISBN: 0195092716
Size: 30.85 MB
Format: PDF, Mobi
View: 1655
Download
This work provides a unified theory that addresses the important problem of the origin and maintenance of genetic variation in natural populations. With modern molecular techniques, variation is found in all species, sometimes at astonishingly high levels. Yet, despite these observations, the forces that maintain variation within and between species have been difficult subjects of study. Because they act very weakly and operate over vast time scales, scientists must rely on indirect inferences and speculative mathematical models. However, despite these obstacles, many advances have been made. The author's research in molecular genetics, evolution, and bio-mathematics has enabled him to draw on this work, and present a coherent and valuable view of the field. The book is divided into three parts. The first consists of three chapters on protein evolution, DNA evolution, and molecular mechanisms. This section reviews the experimental observations on genetic variation. The second part gives a unified treatment of the mathematical theory of selection in a fluctuating environment. The final two chapters combine the earlier assessments in a treatment of the scientific status of two competing theories for the maintenance of genetic variation. Steeped in the enormous advances population genetics has made over the past 25 years, this book has proven highly popular among human geneticists, biologists, evolutionary theorists, and bio-mathematicians.

Elements Of Evolutionary Genetics

Author: Brian Charlesworth
Publisher: Roberts Publishers
ISBN:
Size: 64.18 MB
Format: PDF, ePub
View: 7322
Download
Evolutionary genetics considers the causes of evolutionary change and the nature of variability in evolution. The methods of evolutionary genetics are critically important for the analysis and interpretation of the massive datasets on DNA sequence variation and evolution that are becoming available, as well for our understanding of evolution in general. This book shows readers how models of the genetic processes involved in evolution are made (including natural selection, migration, mutation, and genetic drift in finite populations), and how the models are used to interpret classical and molecular genetic data. The material is intended for advanced level undergraduate courses in genetics and evolutionary biology, graduate students in evolutionary biology and human genetics, and researchers in related fields who wish to learn evolutionary genetics. The topics covered include genetic variation, DNA sequence variability and its measurement, the different types of natural selection and their effects (e.g. the maintenance of variation, directional selection, and adaptation), the interactions between selection and mutation or migration, the description and analysis of variation at multiple sites in the genome, genetic drift, and the effects of spatial structure. The final two chapters demonstrate how the theory illuminates our understanding of the evolution of breeding systems, sex ratios and life histories, and some aspects of genome evolution.

Introduction To Population Genetics

Author: Richard Halliburton
Publisher: Benjamin-Cummings Publishing Company
ISBN: 9780130163806
Size: 69.82 MB
Format: PDF, ePub, Mobi
View: 6057
Download
Making the theory of population genetics relevant to readers, this book explains the related mathematics with a logical organization.It presents the quantitative aspects of population genetics, and employs examples of human genetics, medical evolution, human evolution, and endangered species.For an introduction to, and understanding of, population genetics.

Evolution And Selection Of Quantitative Traits

Author: Bruce Walsh
Publisher: Oxford University Press
ISBN: 0192566644
Size: 80.73 MB
Format: PDF, ePub, Mobi
View: 2106
Download
Quantitative traits-be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene-usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters and is based on mathematical models of evolution in which many genes influence the trait and in which non-genetic factors may also be important. Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, showing the interplay between theory and data with extensive discussions on statistical issues relating to the estimation of the biologically relevant parameters for these models. Quantitative genetics is viewed as the bridge between complex mathematical models of trait evolution and real-world data, and the authors have clearly framed their treatment as such. This is the second volume in a planned trilogy that summarizes the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields (agriculture, evolution, ecology, and human biology) as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics. Whilst volume 1 (1998) dealt with the genetics of such traits, the main focus of volume 2 is on their evolution, with a special emphasis on detecting selection (ranging from the use of genomic and historical data through to ecological field data) and examining its consequences.

Molecular Population Genetics

Author: Matthew William Hahn
Publisher: Sinauer Associates, Incorporated
ISBN: 9780878939657
Size: 35.61 MB
Format: PDF, ePub, Mobi
View: 4124
Download
Molecular Population Genetics is a general text covering one of the most active and exciting areas in biology. Combining advances in molecular biology and genomics with mathematical and empirical findings from population genetics, work in molecular population genetics has uncovered the extraordinary history of natural selection and demographic shifts in many organisms, including humans. While basic descriptions of the methods and tools of this field can be found in disparate places, no previous book has brought them together in a single volume. Rather than cobble together pieces from books, reviews, and primary research articles, Molecular Population Genetics presents a coherent user's guide to the field. Intended as a text for upper-level undergraduate and graduate students, the book will also be useful as a detailed reference for active professionals.

Understanding Population Genetics

Author: Torbjörn Säll
Publisher: John Wiley & Sons
ISBN: 1119124034
Size: 73.43 MB
Format: PDF
View: 1235
Download
Interpretations, extensions and comments -- Altruism and natural selection via individuals and groups -- Frequency-dependent selection and resource competition -- Rare allele advantage due to infections and self-incompatibility -- Questions -- Chapter 9 Selection on a quantitative trait -- Analysis -- Selection in quantitative genetics -- Selection in population genetics - one more time -- Notations and assumptions -- Combining the tools -- Summing up -- Interpretations, extensions and comments -- The genetic effect of selection on a quantitative trait -- The limits of selection and the nature of -- Threshold selection and disease liability -- Quantitative genetics is not suited for causal analyses -- Chapter 10 Evolutionary genetic analysis of the sex ratio -- Analysis -- Assumptions and notations -- Finding the recursion equation system -- Testing for stability -- Summing up -- Interpretations, extensions and comments -- Sex ratio selection -- An explanation of well-delimited validity -- Meiotic recombination is an evolved genetic system -- Evolutionary genetic analysis -- What's next? -- Estimates and tests in population genetics -- The mutation-selection balance -- Partial genetic isolation -- Segregation distortion and genetic conflicts -- Epilogue -- Thanks -- Glossary -- Answers -- References -- Index -- EULA