Pharmaceutical Statistics

Author: Sanford Bolton
Publisher: Marcel Dekker
ISBN: 0824746953
Size: 50.55 MB
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The fourth edition of a bestselling text, this book covers the use of statistics in pharmaceutical research and clinical evaluation. It includes a disk with special prograns to aid in problem analysis. The coverage progresses from basic definitions and concepts, data graphics, and probability through ANOVA, factorial designs, and optimization techniques. The discussion and examples have been expanded to include GMPs, validation, and quality control, as well as procedures and analyses in bioequivalence studies. The text presents fresh material on concept conformity and release targets and describes linear regression and correlation, the analysis of variance, and crossover designs.

Pharmaceutical Statistics

Author: Sanford Bolton
Publisher: CRC Press
ISBN: 1420074237
Size: 17.74 MB
Format: PDF
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Through the use of practical examples and solutions, Pharmaceutical Statistics: Practical and Clinical Applications, Fifth Edition provides the most complete and comprehensive guide to the various statistical applications and research issues in the pharmaceutical industry, particularly in clinical trials and bioequivalence studies.

Pharmaceutical Statistics

Author: Sanford Bolton
Publisher: Marcel Dekker Incorporated
ISBN: 9780824782672
Size: 60.45 MB
Format: PDF
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For pharmacists and health science-related scientists who want to learn statistics. Requires no previous statistical education or math beyond basic arithmetic. Annotation(c) 2003 Book News, Inc., Portland, OR (booknews.com)

Microencapsulation

Author: Simon Benita
Publisher: CRC Press
ISBN: 9781420027990
Size: 25.82 MB
Format: PDF, Kindle
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Presenting breakthrough research pertinent to scientists in a wide range of disciplines-from medicine and biotechnology to cosmetics and pharmacy-this Second Edition provides practical approaches to complex formulation problems encountered in the development of particulate delivery systems at the micro- and nano-size level. Completely revised and expanded to represent the most up-to-date studies in the field, this guide covers advances in pulsatile delivery systems, injectable microparticulate systems, and site-specific delivery systems, as well as potential therapeutic applications of nanotechnology.

Radiopharmaceuticals

Author: AdrainD. Nunn
Publisher: Routledge
ISBN: 1351419897
Size: 64.69 MB
Format: PDF
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This timely resource compares single-photon emission tomography (SPECT), used mainly withTechnetium and iodine for routine clinical examinations, and positron emission tomography(PET) , employing short-lived radionuclides of carbon, oxygen, nitrogen, and fluorine in researchinvestigations.Presenting the logic behind why one approach is better than another in various circumstances,Radio pharmaceuticals details the use of radiolabelled substrates in measuring the effect of diseaseand drugs on regional metabolism and receptor concentration/occupancy .. . discusses factorsaffecting the selective retention of small metal complexes by various tissues .. . analyzes the interactionof small exogenous metal complexes with enzymes in vivo and the critical role of stereochemistry. . . explores the use of radio labelled compounds in the study of neuroactive compounds,neurotransmitters, enzyme inhibitors, and substrates in vivo .. . covers the design and pharmacologyof radiolabelled drugs as probes of site of action , selectivity and specificity, and pharmacokineticsin vivo .. . and more.Extensively referenced with over l 050 bibliographic citations, Radiopharmaceuticals is a state-ofthe-art guide for pharmacists; organic, medicinal , and radiopharmaceutical chemists; pharmacokineticists;nuclear medicine physicians and technologists; neurochemists; and governmentregulatory personnel .

Dermatological And Transdermal Formulations

Author: Kenneth A. Walters
Publisher: CRC Press
ISBN: 9780824743239
Size: 28.51 MB
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Containing 350 illustrations, tables, and equations and covering AAPS/FDA guidelines for the experimentation and analysis of in vivo and in vitro percutaneous absorption, this reference provides comprehensive coverage of the development, preparation, and application of topical and transdermal therapeutic systems. Recognized international experts discuss the bioequivalence of dermatological and transdermal dosage forms. They explore the biochemistry and treatment of skin diseases, the structure and function of the skin, adverse dermal responses to drug formulations, mechanisms of drug transport through barrier membranes, and methods for measuring and modulating percutaneous permeation.

Percutaneous Absorption

Author: Robert L. Bronaugh
Publisher: CRC Press
ISBN: 9781420000948
Size: 64.64 MB
Format: PDF, Kindle
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Since publication of the Second Edition in 1989, numerous innovations have occurred that affect the way scientists look at issues in the field of percutaneous absorption. Focusing on recent advances as well as updating and expanding the scope of topics covered in the previous edition, Percutaneous Absorption, Third Edition provides thorough coverage of the skin's role as an important portal of entry for chemicals into the body. Assembles the work of nearly 80 experts-30 more than the Second Edition-into a unified, comprehensive volume that contains the latest ideas and research! Complete with nearly 600 drawings, photographs, equations, and tables and more than 1600 bibliographic citations of pertinent literature, Percutaneous Absorption, Third Edition details the applied biology of percutaneous penetration factors that affect skin permeation, such as age, vehicles, metabolism, hydration of skin, and chemical structure in vivo and in vitro techniques for measuring absorption, examining factors influencing methodology such as animal models, volatility of test compound, multiple dosage, and artificial membranes procedures for use in transdermal delivery, exploring topics such as effects of penetration enhancers on absorption, optimizing absorption, and the topical delivery of drugs to muscle tissue And presents new chapters on mathematical models cutaneous metabolism prediction of percutaneous absorption in vitro absorption methodology dermal decontamination concentration of chemicals in skin transdermal drug delivery mechanisms of absorption safety evaluation of cosmetics absorption of drugs and cosmetic ingredients nail penetration Emphasizes human applications-particularly useful for pharmacists, pharmacologists, dermatologists, cosmetic scientists, biochemists, toxicologists, public health officials, manufacturers of cosmetic and toiletry products, and graduate students in these disciplines! An invaluable reference source for readers who need to keep up with the latest developments in the field, Percutaneous Absorption, Third Edition is also an excellent experimental guide for laboratory personnel.

Pharmaceutical Inhalation Aerosol Technology Second Edition

Author: Anthony J. Hickey
Publisher: CRC Press
ISBN: 9780824756642
Size: 76.68 MB
Format: PDF, Mobi
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This thoroughly revised and expanded reference provides authoritative discussions on the physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors, influencing the efficacy and utilization of pharmaceutical aerosol. It analyzes the latest science and developments in the generation, administration and characterization of these compounds, showcasing current clinical applications, the efficiency and limitations of major aerosol products and emerging aerosol therapies impacting the field.

Mechanisms Of Transdermal Drug Delivery

Author: Russel O. Potts
Publisher: CRC Press
ISBN: 9781420002249
Size: 79.87 MB
Format: PDF
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Provides an up-to-date and critical examination of biophysical techniques used in the analysis of molecular mechanisms underlying transdermal drug delivery as well as a physical and chemical evaluation of the stratum corneum necessary for the enhancement of percutaneous drug transport. Reflects the hands-on experience of established and novel researchers in the field.

Microencapsulation

Author: Simon Benita
Publisher: CRC Press
ISBN: 9781420027990
Size: 11.41 MB
Format: PDF, Mobi
View: 6907
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Presenting breakthrough research pertinent to scientists in a wide range of disciplines-from medicine and biotechnology to cosmetics and pharmacy-this Second Edition provides practical approaches to complex formulation problems encountered in the development of particulate delivery systems at the micro- and nano-size level. Completely revised and expanded to represent the most up-to-date studies in the field, this guide covers advances in pulsatile delivery systems, injectable microparticulate systems, and site-specific delivery systems, as well as potential therapeutic applications of nanotechnology.