Pediatric Biomedical Informatics

Author: John J. Hutton
Publisher: Springer Science & Business Media
ISBN: 9400751494
Size: 46.34 MB
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Advances in the biomedical sciences, especially genomics, proteomics, and metabolomics, taken together with the expanding use of electronic health records, are radically changing the IT infrastructure and software applications needed to support the transfer of knowledge from bench to bedside. Pediatric Biomedical Informatics: Computer Applications in Pediatric Research describes the core resources in informatics necessary to support biomedical research programs and how these can best be integrated with hospital systems to receive clinical information that is necessary to conduct translational research.The focus is on the authors’ recent practical experiences in establishing an informatics infrastructure in a large research-intensive children’s hospital. This book is intended for translational researchers and informaticians in pediatrics, but can also serve as a guide to all institutions facing the challenges of developing and strengthening informatics support for biomedical research. The first section of the book discusses important technical challenges underlying computer-based pediatric research, while subsequent sections discuss informatics applications that support biobanking and a broad range of research programs. Pediatric Biomedical Informatics provides practical insights into the design, implementation, and utilization of informatics infrastructures to optimize care and research to benefit children. Dr. John Hutton is the Vice President and Director of Biomedical Informatics at Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA. He is also Professor of Pediatrics and Associate Dean for Information Services at the University of Cincinnati College of Medicine.

Applied Computational Genomics

Author: Yin Yao Shugart
Publisher: Springer Science & Business Media
ISBN: 9400755589
Size: 50.13 MB
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"Applied Computational Genomics" focuses on an in-depth review of statistical development and application in the area of human genomics including candidate gene mapping, linkage analysis, population-based, genome-wide association, exon sequencing and whole genome sequencing analysis. The authors are extremely experienced in the area of statistical genomics and will give a detailed introduction of the evolution in the field and critical evaluations of the advantages and disadvantages of the statistical models proposed. They will also share their views on a future shift toward translational biology. The book will be of value to human geneticists, medical doctors, health educators, policy makers, and graduate students majoring in biology, biostatistics, and bioinformatics. Dr. Yin Yao Shugart is investigator in the Intramural Research Program at the National Institute of Mental Health, Bethesda, Maryland USA. ​

Application Of Clinical Bioinformatics

Author: Xiangdong Wang
Publisher: Springer
ISBN: 9401775435
Size: 69.25 MB
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This book elucidates how genetic, biological and medical information can be applied to the development of personalized healthcare, medication and therapies. Focusing on aspects of the development of evidence-based approaches in bioinformatics and computational medicine, including data integration, methodologies, tools and models for clinical and translational medicine, it offers an essential introduction to clinical bioinformatics for clinical researchers and physicians, medical students and teachers, and scientists working with human disease-based omics and bioinformatics. Dr. Xiangdong Wang is a distinguished Professor of Medicine. He is Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Deputy Director of Shanghai Respiratory Research Institute, Director of Biomedical Research Center, Fudan University Zhongshan Hospital, Shanghai, China; Dr. Christian Baumgartner is a Professor of Health Care and Biomedical Engineering at Institute of Health Care Engineering with European Notified Body of Medical Devices, Graz University of Technology, Graz, Austria; Dr. Denis Shields is a Professor of Clinical Bioinformatics at Conway Institute, Belfield, Dublin, Ireland; Dr. Hong-Wen Deng is a Professor at Department of Biostatistics and Bioinformatics, Tulane University School of Public Health and Tropical Medicine, USA; Dr. Jacques S Beckmann is a Professor and Director of Section of Clinical Bioinformatics, Swiss Institute of Bioinformatics, Switzerland.

Biomedical Informatics

Author: Edward H. Shortliffe
Publisher: Springer Science & Business Media
ISBN: 1447144740
Size: 12.53 MB
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The practice of modern medicine and biomedical research requires sophisticated information technologies with which to manage patient information, plan diagnostic procedures, interpret laboratory results, and carry out investigations. Biomedical Informatics provides both a conceptual framework and a practical inspiration for this swiftly emerging scientific discipline at the intersection of computer science, decision science, information science, cognitive science, and biomedicine. Now revised and in its third edition, this text meets the growing demand by practitioners, researchers, and students for a comprehensive introduction to key topics in the field. Authored by leaders in medical informatics and extensively tested in their courses, the chapters in this volume constitute an effective textbook for students of medical informatics and its areas of application. The book is also a useful reference work for individual readers needing to understand the role that computers can play in the provision of clinical services and the pursuit of biological questions. The volume is organized so as first to explain basic concepts and then to illustrate them with specific systems and technologies.

Big Data Analysis For Bioinformatics And Biomedical Discoveries

Author: Shui Qing Ye
Publisher: CRC Press
ISBN: 149872454X
Size: 22.96 MB
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Demystifies Biomedical and Biological Big Data Analyses Big Data Analysis for Bioinformatics and Biomedical Discoveries provides a practical guide to the nuts and bolts of Big Data, enabling you to quickly and effectively harness the power of Big Data to make groundbreaking biological discoveries, carry out translational medical research, and implement personalized genomic medicine. Contributing to the NIH Big Data to Knowledge (BD2K) initiative, the book enhances your computational and quantitative skills so that you can exploit the Big Data being generated in the current omics era. The book explores many significant topics of Big Data analyses in an easily understandable format. It describes popular tools and software for Big Data analyses and explains next-generation DNA sequencing data analyses. It also discusses comprehensive Big Data analyses of several major areas, including the integration of omics data, pharmacogenomics, electronic health record data, and drug discovery. Accessible to biologists, biomedical scientists, bioinformaticians, and computer data analysts, the book keeps complex mathematical deductions and jargon to a minimum. Each chapter includes a theoretical introduction, example applications, data analysis principles, step-by-step tutorials, and authoritative references.

Translational Biomedical Informatics

Author: Bairong Shen
Publisher: Springer
ISBN: 9811015031
Size: 43.73 MB
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This book introduces readers to essential methods and applications in translational biomedical informatics, which include biomedical big data, cloud computing and algorithms for understanding omics data, imaging data, electronic health records and public health data. The storage, retrieval, mining and knowledge discovery of biomedical big data will be among the key challenges for future translational research. The paradigm for precision medicine and healthcare needs to integratively analyze not only the data at the same level – e.g. different omics data at the molecular level – but also data from different levels – the molecular, cellular, tissue, clinical and public health level. This book discusses the following major aspects: the structure of cross-level data; clinical patient information and its shareability; and standardization and privacy. It offers a valuable guide for all biologists, biomedical informaticians and clinicians with an interest in Precision Medicine Informatics.

Clinical Research Informatics

Author: Rachel Richesson
Publisher: Springer Science & Business Media
ISBN: 1848824483
Size: 34.78 MB
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The purpose of the book is to provide an overview of clinical research (types), activities, and areas where informatics and IT could fit into various activities and business practices. This book will introduce and apply informatics concepts only as they have particular relevance to clinical research settings.

Pediatric Informatics

Author: Christoph Lehmann
Publisher: Springer Science & Business Media
ISBN: 0387764461
Size: 79.91 MB
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Now is a critical time in pediatric informatics. As information technologies—electronic health records (EHRs), personal health records (PHRs), computerized physician order entry (CPOE)—and standards (HL7) are developed to improve the quality of health care, it is imperative for policy makers and pediatricians to be aware of their impact on pediatric care and child health. Informed child advocates must be at the planning table as national and regional health information networks are developed to insure the unique health care needs of children are being met. Pediatric Informatics: Computer Applications in Child Health is a current digest of the important trends in pediatric informatics, written by leading experts in the field. This book explores how the management of biomedical data, information, and knowledge can optimize and advance child health. The contributors investigate the specific importance of pediatric informatics is derived from the biological, psychological, social and cultural needs that the distinguish children from other populations. These distinctions create complexities in the management of pediatric data and information that make children a vulnerable population and require the development of a new body of knowledge in pediatric informatics.

Biomedical Informatics

Author: Edward H. Shortliffe
Publisher: Springer Science & Business Media
ISBN: 1447144740
Size: 53.30 MB
Format: PDF, Kindle
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The practice of modern medicine and biomedical research requires sophisticated information technologies with which to manage patient information, plan diagnostic procedures, interpret laboratory results, and carry out investigations. Biomedical Informatics provides both a conceptual framework and a practical inspiration for this swiftly emerging scientific discipline at the intersection of computer science, decision science, information science, cognitive science, and biomedicine. Now revised and in its third edition, this text meets the growing demand by practitioners, researchers, and students for a comprehensive introduction to key topics in the field. Authored by leaders in medical informatics and extensively tested in their courses, the chapters in this volume constitute an effective textbook for students of medical informatics and its areas of application. The book is also a useful reference work for individual readers needing to understand the role that computers can play in the provision of clinical services and the pursuit of biological questions. The volume is organized so as first to explain basic concepts and then to illustrate them with specific systems and technologies.

Avery S Diseases Of The Newborn E Book

Author: Christine A. Gleason
Publisher: Elsevier Health Sciences
ISBN: 0323401724
Size: 46.65 MB
Format: PDF, Kindle
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Covering the evaluation and management of every key disease and condition affecting newborns, Avery’s Diseases of the Newborn, by Drs. Christine A. Gleason and Sandra E. Juul, remains your #1 source for practical, clinically relevant information in this fast-changing field. You’ll find the specific strategies you need to confidently diagnose and treat this unique patient population, in a full-color, easy-to-use single volume that focuses on key areas of practice. Now in a thoroughly revised 10th Edition, this highly respected reference is an authoritative clinical resource for neonatal practitioners. Provides up-to-date information on every aspect of newborn evaluation and management in a new, visually improved format featuring more than 500 all-new, full-color illustrations integrated within each chapter. Includes greatly expanded Neurology and Hematology sections that highlight the knowledge and expertise of new co-editor, Dr. Sandra E. Juul. Features all-new chapters on Palliative Care, Gastroesophageal Reflux, Platelet Disorders, Transfusion Therapy, Hypertension, , and The Ear and Hearing Disorders, as well as expanded coverage of brain injury and neuroprotective strategies in the preterm and term infant. Contains new Key Points boxes at the beginning of every chapter. Brings you up to date on current topics such as the evolving epidemic of neonatal abstinence syndrome and the new clinical uses of ultrasound.