Multi Axial Fatigue Of Trabecular Bone With Respect To Normal Walking

Author: Mohammad Mostakhdemin
Publisher: Springer
ISBN: 9812876219
Size: 19.72 MB
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This book focuses on the analysis and treatment of osteoporotic bone based on drug administration, tracking fatigue behavior and taking into consideration the mechanical interaction of implants with trabecular bone. Weak trabeculae are one of the most important clinical features that need to be addressed in order to prevent hip joint fractures.

The Neuromuscular System From Earth To Space Life Science

Author: Dieter Blottner
Publisher: Springer
ISBN: 3319122983
Size: 21.83 MB
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The book provides fundamental new insights in the structure and function of the healthy NeuroMuscular system. Recent findings suggest that the musculoskeletal system that supports movement control on Earth is controlled by unique principles of structural, biochemical and molecular characteristics. Mechanical loading by working against normal gravity helps to support principal structures in bone, muscle and associated subcellular scaffold components. Disuse or immobilization of the body in bed rest on Earth or in microgravity in Space result in considerable loss of bone, muscle and force with downregulation of neuromuscular activity resulting in impaired performance control. The goal is to develop exercise prescriptions to maintain postural control in normal life, aging and rehabilitation on Earth as well as for an adequate human performance management in Space.

Data Driven Process Discovery And Analysis

Author: Karl Aberer
Publisher: Springer
ISBN: 364234044X
Size: 58.60 MB
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This book constitutes the thoroughly refereed proceedings of the First International Symposium on Data-Driven Process Discovery and Analysis held in Campione d'Italia, Italy, in June/July 2011. The 11 revised full papers were carefully selected from 31 submissions. In addition to the thorough review process, the lively discussions at the event itself also helped the authors to improve their papers and to foster interesting extensions. The selected papers cover a wide range of topics spanning from theoretical issues related to process representation to practical experience in process discovery and analysis.

Apley And Solomon S Concise System Of Orthopaedics And Trauma Fourth Edition

Author: Louis Solomon
Publisher: CRC Press
ISBN: 1444174320
Size: 31.31 MB
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Apley and Solomon’s Concise System of Orthopaedics and Trauma is firmly established as the leading introductory textbook of orthopaedic practice and the principles of fracture management. Praised in previous editions for its systematic approach, balanced content and easy-to-read style, the fourth edition has been brought fully up to date with more than 800 illustrations, many new to this edition, providing an invaluable pictorial account of this highly visual subject. Key features of the Fourth Edition: Reflects the changing pattern of musculoskeletal disease around the world Focuses on actual diseases and clinical signs, with additional coverage of anatomy where appropriate—ideal for the medical student and junior surgeon Provides helpful guidance on simple procedures without unnecessary operative detail Includes revised and expanded sections on developments in molecular biology and genetics—reflecting the growing clinical significance of these important areas Demonstrates new imaging technologies Retains popular features such as handy check points and text boxes—ideal for rapid assimilation during a clinical placement or exam revision This text remains the first choice for medical students, trainee surgeons and other health professionals seeking a concise introduction to this large and complex subject. It is a natural preface to the more detailed coverage offered by the parent book, Apley’s System of Orthopaedics and Trauma.

Neurodynamics An Exploration In Mesoscopic Brain Dynamics

Author: Walter Freeman
Publisher: Springer Science & Business Media
ISBN: 9781852336165
Size: 28.48 MB
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Cortical evoked potentials are of interest primarily as tests of changing neuronal excitabilities accompanying normal brain function. The first three steps in the anal ysis of these complex waveforms are proper placement of electrodes for recording, the proper choice of electrical or sensory stimulus parameters, and the establish ment of behavioral control. The fourth is development of techniques for reliable measurement. Measurement consists of comparison of an unknown entity with a set of standard scales or dimensions having numerical attributes in preassigned degree. A physical object can be described by the dimensions of size, mass, density, etc. In addition there are dimensions such as location, velocity, weight, hardness, etc. Some of these dimensions can be complex (e. g. size depends on three or more subsidiary coordi nates), and some can be interdependent or nonorthogonal (e. g. specification of size and mass may determine density). In each dimension the unit is defined with refer ence to a standard physical entity, e. g. a unit of mass or length, and the result of measurement is expressed as an equivalence between the unknown and the sum of a specified number of units of that entity. The dimensions of a complex waveform are elementary waveforms from which that waveform can be built by simple addition. Any finite single-valued function of time is admissible. They are called basis functions (lO, 15), and they can be expressed in numeric as well as geometric form.

Sphingolipids Basic Science And Drug Development

Author: Erich Gulbins
Publisher: Springer Science & Business Media
ISBN: 3709113687
Size: 21.58 MB
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Sphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. This book on sphingolipids provides insights into the basics of sphingolipid biology and drug development, with a particular emphasis on the sphingolipid derivative ceramide. In the first part basic functions of sphingolipids are described, as well as the genetics of important enzymes, sphingolipid metabolism and synthesis. The second part of this first volume focuses on drug development and pharmacology. The book is intended for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians working in pharmacology, oncology, cardiology, neurology and infectious disease. Together with Volume 216 by the same editors, the collection represents a unique, comprehensive work on sphingolipids, providing information on both sphingolipids’ basic biology (including synthesis, metabolism and cell biology) and their important function in a (patho-)physiological context.

Bone Pathology

Author: Jasvir S. Khurana
Publisher: Springer Science & Business Media
ISBN: 9781597453479
Size: 30.75 MB
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Bone Pathology is the second edition of the book, A Compendium of Skeletal Pathology that published 10 years ago. Similar to the prior edition, this book complements standard pathology texts and blends new but relatively established information on the molecular biology of the bone. Serving as a bench-side companion to the surgical pathologist, this new edition reflects new advances in our understanding of the molecular biology of bone. New chapters on soft-tissue sarcomas and soft-tissue tumors have been added as well as several additional chapters such as Soft-tissue pathology and Biomechanics. The volume is written by experts who are established in the field of musculoskeletal diseases. Bone Pathology is a combined effort from authors of different specialties including surgeons, pathologists, radiologists and basic scientists all of whom have in common an interest in bone diseases. It will be of great value to surgical pathology residents as well as practicing pathologists, skeletal radiologists, orthopedic surgeons and medical students.

Translational Informatics In Smart Healthcare

Author: Bairong Shen
Publisher: Springer
ISBN: 9811057176
Size: 62.64 MB
Format: PDF
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This book is about the transformation of the biomedical information to smart healthcare, the chapters are designed to discuss the health associated factors such as genetics, lifestyle, nutrition and environmental factors. The interactions of these factors and the informatics for the analyses of their effects on health are also covered. The era of aging is approaching and the P4 (predictive, preventive, personalized and participatory) medicine paradigm is becoming practical and reality. According to the Kondratiev's long wave theory, IT (information technology) and health will be the next technological revolution for the new economic cycle. This book is written for biomedical informatics scientists, clinicians, health practitioners and researchers, etc.

Technologies For Medical Sciences

Author: Renato Natal Jorge
Publisher: Springer Science & Business Media
ISBN: 9400740689
Size: 54.90 MB
Format: PDF, Mobi
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This book presents novel and advanced technologies for medical sciences in order to solidify knowledge in the related fields and define their key stakeholders. The fifteen papers included in this book were written by invited experts of international stature and address important technologies for medical sciences, including: computational modeling and simulation, image processing and analysis, medical imaging, human motion and posture, tissue engineering, design and development medical devices, and mechanic biology. Different applications are treated in such diverse fields as biomechanical studies, prosthesis and orthosis, medical diagnosis, sport, and virtual reality. This book is of interest to researchers, students and manufacturers from a wide range of disciplines related to bioengineering, biomechanics, computational mechanics, computational vision, human motion, mathematics, medical devices, medical image, medicine and physics.

Introduction To Evolutionary Genomics

Author: Naruya Saitou
Publisher: Springer Science & Business Media
ISBN: 1447153049
Size: 24.52 MB
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This book is the first of its kind to explain the fundamentals of evolutionary genomics. The comprehensive coverage includes concise descriptions of a variety of genome organizations, a thorough discussion of the methods used, and a detailed review of genome sequence processing procedures. The opening chapters also provide the necessary basics for readers unfamiliar with evolutionary studies. Features: introduces the basics of molecular biology, DNA replication, mutation, phylogeny, neutral evolution, and natural selection; presents a brief evolutionary history of life from the primordial seas to the emergence of humans; describes the genomes of prokaryotes, eukaryotes, vertebrates, and humans; reviews methods for genome sequencing, phenotype data collection, homology searches and analysis, and phylogenetic tree and network building; discusses databases of genome sequences and related information, evolutionary distances, and population genomics; provides supplementary material at an associated website.