Modern Computational Approaches To Traditional Chinese Medicine

Author: Zhaohui Wu
Publisher: Elsevier
ISBN: 0123985196
Size: 44.15 MB
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Recognized as an essential component of Chinese culture, Traditional Chinese Medicine (TCM) is both an ancient medical system and one still used widely in China today. TCM’s independently evolved knowledge system is expressed mainly in the Chinese language and the information is frequently only available through ancient classics and confidential family records, making it difficult to utilize. The major concern in TCM is how to consolidate and integrate the data, enabling efficient retrieval and discovery of novel knowledge from the dispersed data. Computational approaches such as data mining, semantic reasoning and computational intelligence have emerged as innovative approaches for the reservation and utilization of this knowledge system. Typically, this requires an inter-disciplinary approach involving Chinese culture, computer science, modern healthcare and life sciences. This book examines the computerization of TCM information and knowledge to provide intelligent resources and supporting evidences for clinical decision-making, drug discovery, and education. Recent research results from the Traditional Chinese Medicine Informatics Group of Zhejiang University are presented, gathering in one resource systematic approaches for massive data processing in TCM. These include the utilization of modern Semantic Web and data mining methods for more advanced data integration, data analysis and integrative knowledge discovery. This book will appeal to medical professionals, life sciences students, computer scientists, and those interested in integrative, complementary, and alternative medicine. Interdisciplinary book bringing together Traditional Chinese Medicine and computer scientists Introduces novel network technologies to Traditional Chinese Medicine informatics Provides theory and practical examples and case studies of new techniques

Serum Pharmacochemistry Of Traditional Chinese Medicine

Author: Xijun Wang
Publisher: Academic Press
ISBN: 0128111488
Size: 62.64 MB
Format: PDF, ePub
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Serum Pharmacochemistry of Traditional Chinese Medicine: Technologies, Strategies and Applications provides a valuable and indispensable guide on the latest methods, research advances, and applications in this area. Chapters offer cutting-edge information on pharmacokinetics and pharmacodynamics, analytical chemistry, traditional medicine, natural products, bioinformatics, new technologies, therapeutic applications, and more. For researchers and students in academia and industry, this book provides a hands-on description of experimental techniques, along with beneficial guidelines to help advance research in the fields of Traditional Chinese Medicine and drug development. Provides a valuable guide for practitioners of serum pharmacochemistry of Traditional Chinese Medicine, along with insights to its current use and future applications Edited and written by leading scientists at the forefront of this research Presents well written chapters that include an introduction, description of the method, and identification of chemical constituents, with applications and references to the latest research and literature

Integrative Approaches For Health

Author: Bhushan Patwardhan
Publisher: Academic Press
ISBN: 0128014342
Size: 64.25 MB
Format: PDF, Kindle
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Despite spectacular advances, modern medicine faces formidable global challenges in several key areas—notably the persistence of major killer diseases such as malaria, tuberculosis, leprosy, and newer threats including HIV/AIDS, resistant infections, and Ebola. As such, modern medicine has not led to a significant decrease in chronic diseases like diabetes, obesity, and other degenerative and autoimmune diseases. The authors believe that modern medicine needs to experience a paradigm shift, an integration of traditions—in particular from the ancient systems like Ayurveda and Yoga. Integrative Approaches for Health: Biomedical Research, Ayurveda and Yoga brings together the basic principles of interdisciplinary systems approach for an evolving construct of future medicine. Such an approach is already emerging at the cutting edge of current research in omics, bioinformatics, computational and systems biology. Several leading institutions of medicine have adopted Yoga and complementary medicine to widen their reach, and deepen effectiveness in therapeutic practices. The amalgam of modern medicine, with its strengths in scientific rigor, blended with the basic principles of life drawn from Ayurveda and Yoga might evolve into a medicine of tomorrow. Integrative approaches are no longer alternative, perhaps taking these approaches is the only possible way to heal our sick planet. This book introduces important trends and tools for biomedical researchers and physicians alike, to innovate the practice of medicine for the better. Contains a harmonious confluence of ancient and modern concepts, historical perspectives, philosophical underpinnings, and a relevant review of literature supported by worldwide case studies. Provides a critical analysis of ancient wisdom, pointing to potential areas for future research, which provide food for thought for public debate on integrative health care for the twenty-first century. Explains Ayurveda knowledge, and its relevance to drug discovery, nutrition, genomics, epigenetics, regenerative biology, longevity and personalized medicine. Shares Yoga knowledge insights, and explains its relevance to body–mind complex relationships, psychology, neurobiology, immunoendocrinology, bioenergetics, consciousness, and cognitive sciences. Offers illustrations and logic diagrams for enhanced understanding of the concepts presented.

Comprehensive Biomedical Physics

Author:
Publisher: Newnes
ISBN: 0444536337
Size: 69.65 MB
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Comprehensive Biomedical Physics is a new reference work that provides the first point of entry to the literature for all scientists interested in biomedical physics. It is of particularly use for graduate and postgraduate students in the areas of medical biophysics. This Work is indispensable to all serious readers in this interdisciplinary area where physics is applied in medicine and biology. Written by leading scientists who have evaluated and summarized the most important methods, principles, technologies and data within the field, Comprehensive Biomedical Physics is a vital addition to the reference libraries of those working within the areas of medical imaging, radiation sources, detectors, biology, safety and therapy, physiology, and pharmacology as well as in the treatment of different clinical conditions and bioinformatics. This Work will be valuable to students working in all aspect of medical biophysics, including medical imaging and biomedical radiation science and therapy, physiology, pharmacology and treatment of clinical conditions and bioinformatics. The most comprehensive work on biomedical physics ever published Covers one of the fastest growing areas in the physical sciences, including interdisciplinary areas ranging from advanced nuclear physics and quantum mechanics through mathematics to molecular biology and medicine Contains 1800 illustrations, all in full color

Molecular Diagnostics And Treatment Of Pancreatic Cancer

Author: Asfar Azmi
Publisher: Elsevier
ISBN: 0124079466
Size: 10.21 MB
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Molecular Diagnostics and Treatment of Pancreatic Cancer describes the different emerging applications of systems biology and how it is shaping modern pancreatic cancer research. This book begins by introducing the current state of the art knowledge, trends in diagnostics, progress in disease model systems as well as new treatment and palliative care strategies in pancreatic cancer. Specific sections are dedicated to enlighten the readers to newer discoveries that have emerged from gene expression profiling, proteomics, metabolomics and systems level analyses of pancreatic cancer datasets. First of a kind and novel network strategies to understand oncogenic Kras signaling in pancreatic tumors are presented. The attempts to computationally model and prioritize microRNAs that cause pancreatic cancer resistance are also highlighted. Addressing this important area, Molecular Diagnostics and Treatment of Pancreatic Cancer provides insights into important network evaluation methodologies related to pancreatic cancer related microRNAs targetome. There are dedicated chapters on critical aspects of the evolving yet controversial field of pancreatic cancer stems cells. The work concludes by discussing the applications of network sciences in pancreatic cancer drug discovery and clinical trial design. Encompasses discussion of innovative tools including expression signatures in cell lines, 3D models, animal xenograft models, primary models and patient derived samples, aiding subversion of traditional biology paradigms, and enhancing comprehension across conventional length and temporal scales Coverage includes novel applications in targeted drugs, polypharmacology, network pharmacology and other related drug development arenas – helping researchers in pancreatic cancer drug discovery Summarizes many relevant computational and clinical references from fast-evolving literature Comprehensive glossary helps newer readers understand technical terms and specialized nomenclature

Neurobiology Of Language

Author: Gregory Hickok
Publisher: Academic Press
ISBN: 0124078621
Size: 15.38 MB
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Neurobiology of Language explores the study of language, a field that has seen tremendous progress in the last two decades. Key to this progress is the accelerating trend toward integration of neurobiological approaches with the more established understanding of language within cognitive psychology, computer science, and linguistics. This volume serves as the definitive reference on the neurobiology of language, bringing these various advances together into a single volume of 100 concise entries. The organization includes sections on the field's major subfields, with each section covering both empirical data and theoretical perspectives. "Foundational" neurobiological coverage is also provided, including neuroanatomy, neurophysiology, genetics, linguistic, and psycholinguistic data, and models. Foundational reference for the current state of the field of the neurobiology of language Enables brain and language researchers and students to remain up-to-date in this fast-moving field that crosses many disciplinary and subdisciplinary boundaries Provides an accessible entry point for other scientists interested in the area, but not actively working in it – e.g., speech therapists, neurologists, and cognitive psychologists Chapters authored by world leaders in the field – the broadest, most expert coverage available

Philosophy Of Complex Systems

Author:
Publisher: Elsevier
ISBN: 9780080931227
Size: 14.37 MB
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The domain of nonlinear dynamical systems and its mathematical underpinnings has been developing exponentially for a century, the last 35 years seeing an outpouring of new ideas and applications and a concomitant confluence with ideas of complex systems and their applications from irreversible thermodynamics. A few examples are in meteorology, ecological dynamics, and social and economic dynamics. These new ideas have profound implications for our understanding and practice in domains involving complexity, predictability and determinism, equilibrium, control, planning, individuality, responsibility and so on. Our intention is to draw together in this volume, we believe for the first time, a comprehensive picture of the manifold philosophically interesting impacts of recent developments in understanding nonlinear systems and the unique aspects of their complexity. The book will focus specifically on the philosophical concepts, principles, judgments and problems distinctly raised by work in the domain of complex nonlinear dynamical systems, especially in recent years. -Comprehensive coverage of all main theories in the philosophy of Complex Systems -Clearly written expositions of fundamental ideas and concepts -Definitive discussions by leading researchers in the field -Summaries of leading-edge research in related fields are also included

Practical Predictive Analytics And Decisioning Systems For Medicine

Author: Linda Miner
Publisher: Academic Press
ISBN: 012411640X
Size: 28.80 MB
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With the advent of electronic medical records years ago and the increasing capabilities of computers, our healthcare systems are sitting on growing mountains of data. Not only does the data grow from patient volume but the type of data we store is also growing exponentially. Practical Predictive Analytics and Decisioning Systems for Medicine provides research tools to analyze these large amounts of data and addresses some of the most pressing issues and challenges where data integrity is compromised: patient safety, patient communication, and patient information. Through the use of predictive analytic models and applications, this book is an invaluable resource to predict more accurate outcomes to help improve quality care in the healthcare and medical industries in the most cost–efficient manner. Practical Predictive Analytics and Decisioning Systems for Medicine provides the basics of predictive analytics for those new to the area and focuses on general philosophy and activities in the healthcare and medical system. It explains why predictive models are important, and how they can be applied to the predictive analysis process in order to solve real industry problems. Researchers need this valuable resource to improve data analysis skills and make more accurate and cost-effective decisions. Includes models and applications of predictive analytics why they are important and how they can be used in healthcare and medical research Provides real world step-by-step tutorials to help beginners understand how the predictive analytic processes works and to successfully do the computations Demonstrates methods to help sort through data to make better observations and allow you to make better predictions

World Century Compendium To Tcm

Author: 'Jin Yang
Publisher: World Scientific
ISBN: 1938134125
Size: 64.82 MB
Format: PDF, ePub
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With increased demands on medical health care due to societal developments, the sole dependence on modern medicine or Western medicine is clearly insufficient. Traditional Chinese medicine, once derided by many in the west, is now firmly in the global limelight due to its numerous advantages in preventing and treating diseases. Chinese medicine achieves its curative effects by making use of natural therapies such as animal and plant parts, which are of interest to many doctors and patients who are in favor of rectifying the entire state of the body. For over two thousand years, Chinese medicinal formulas have been extensively used in China as the main technique to prevent and treat. The accordance of formula and disease pattern is the most specific, objective, stable, and recurrently effective aspect of treatment based on pattern differentiation, which will be introduced in this book as a reliable analytical method. In this book, the fundamental concepts of Chinese medicine, methods of conducting pattern differentiation and composing principles of formulas, and integration of indispensable courses of Chinese medicine, such as basic theories, diagnostic methods, Chinese medicinals, formulas, treatment principles, internal medicine, and warm diseases will be discussed, opening a door for novices who are interested to learn more about Chinese medicine. Through self-study of this book in a relatively short duration, it is our hope that the reader will be familiar with and preliminarily apply the basic theories of Chinese medicine and formulas in practice. This not only serves to prevent and treat diseases, but more importantly, contributes to the spread of traditional Chinese medicine.Contents: Chinese Medicine and MedicinalsPrescribing a Formula in Accordance with the PatternThe Exterior PatternThe Half-Exterior and Half-Interior PatternThe Cold PatternThe Heat PatternThe Phlegm–Rheum and Water–Dampness PatternThe Wind PatternThe Qi Stagnation PatternThe Static Blood PatternThe Food Accumulation PatternThe Wind–Damp PatternThe Deficiency PatternThe Complex PatternFormulae for Diseases of the Respiratory SystemFormulae for Diseases of the Digestive SystemFormulae for Diseases of the Cardiovascular SystemFormulae for Diseases of the Urogenital SystemFormulae for Diseases of the Nervous System Readership: Medical professionals, both Western medical doctors and TCM practitioners, particularly those practicing in Australia, Europe and America; Chinese medicine educators, clinical and basic Chinese medicine researchers and health science students (particularly Chinese medicine students); herbalists, gerontology researchers, nutritionists, public health specialists (health policy departments in ministries of health and universities); professionals at the World Health Organization and affiliated institutions, and pharmaceutical companies; librarians of TCM professional associations and teaching institutes and the lay reader who either wants general knowledge or wishes to understand how TCM can help a friend, relative or loved one.

Comprehensive Materials Processing

Author:
Publisher: Newnes
ISBN: 0080965334
Size: 57.19 MB
Format: PDF, Mobi
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Comprehensive Materials Processing provides students and professionals with a one-stop resource consolidating and enhancing the literature of the materials processing and manufacturing universe. It provides authoritative analysis of all processes, technologies, and techniques for converting industrial materials from a raw state into finished parts or products. Assisting scientists and engineers in the selection, design, and use of materials, whether in the lab or in industry, it matches the adaptive complexity of emergent materials and processing technologies. Extensive traditional article-level academic discussion of core theories and applications is supplemented by applied case studies and advanced multimedia features. Coverage encompasses the general categories of solidification, powder, deposition, and deformation processing, and includes discussion on plant and tool design, analysis and characterization of processing techniques, high-temperatures studies, and the influence of process scale on component characteristics and behavior. Authored and reviewed by world-class academic and industrial specialists in each subject field Practical tools such as integrated case studies, user-defined process schemata, and multimedia modeling and functionality Maximizes research efficiency by collating the most important and established information in one place with integrated applets linking to relevant outside sources