Human Genetic Diversity

Author: Julian C. Knight
Publisher: Oxford University Press on Demand
ISBN: 0199227691
Size: 37.10 MB
Format: PDF
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This book describes the remarkable progress which has been made in defining the extent and nature of human genetic variation. It provides a framework for understanding how research in this area is revolutionising our knowledge of human origins and the genetic basis of disease, as well as common traits such as obesity.

Modern Nutrition In Health And Disease

Author: Maurice Edward Shils
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781741330
Size: 61.46 MB
Format: PDF, ePub
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Distinguished experts provide in-depth information on historic landmarks in nutrition, specific dietary components, nutrition in integrated biologic systems, nutritional assessment through the life cycle, nutrition in various clinical disorders, public health and policy issues, and more.

Tandem Repeat Polymorphisms

Author: Anthony J. Hannan
Publisher: Springer Science & Business Media
ISBN: 1461454344
Size: 42.50 MB
Format: PDF, ePub, Docs
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This book addresses the role of tandem repeat polymorphisms (TRPs) in genetic plasticity, evolution, development, biological processes, neural diversity, brain function, dysfunction and disease. There are hundreds of thousands of unique tandem repeats in the human genome and their polymorphic distributions have the potential to greatly influence functional diversity and disease susceptibility. Recent discoveries in this expanding field are critically reviewed and discussed in a range of subsequent chapters, with a focus on the role of TRPs and their various gene products in evolution, development, diverse molecular and cellular processes, brain function and disease.

Acute Coronary Syndromes A Companion To Braunwald S Heart Disease E Book

Author: Pierre Theroux
Publisher: Elsevier Health Sciences
ISBN: 1437721494
Size: 60.74 MB
Format: PDF, Kindle
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Acute Coronary Syndromes—a Companion to Braunwald’s Heart Disease—covers the state-of-the-art scientific and clinical information you need to rapidly evaluate and manage acute coronary syndromes. Dr. Pierre Theroux and his team of expert contributors present advances in diagnostic and imaging techniques such as biomarkers, nuclear cardiology, echocardiography, and multislice CT; secondary prevention; and new antiplatelet, anti-ischemic, and gene therapies. Tap into the most definitive knowledge available from one of the leading experts in the field and a stellar cast of contributors. Understand the special considerations for the care of acute coronary syndromes in the emergency department and the coronary care unit. Effectively handle the treatment of special populations and chronic patients thanks to coverage of these challenges See techniques and procedures in greater detail and clarity through the all-new full-color design. Approach treatment with a global perspective from the new section on Population-Based Perspective that discusses the INTERHEART study, insights from the REACH registry, lessons learned from European registries, and ACS in North America. Gain a comprehensive understanding of ACS through coverage of pathophysiology, molecular mechanisms, the role of the immune system, and brand-new chapters on cell necrosis and cell regeneration and pharmacogenetics in the section on Disease-Based Perspectives. Integrate the latest testing and treatment techniques into your practice thanks to new chapters on biomarkers in acute ischemic heart disease; the role of noninvasive testing in prognostic risk stratification; the culprit lesions and patient at risk; non-responsiveness to antiplatelet therapy; bleeding in the acute coronary syndromes; and the refractory patient.

Andreoli And Carpenter S Cecil Essentials Of Medicine E Book

Author: Thomas E. Andreoli
Publisher: Elsevier Health Sciences
ISBN: 1437726739
Size: 15.65 MB
Format: PDF, ePub, Mobi
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Students, residents, and instructors swear by Andreoli and Carpenter’s Cecil Essentials of Medicine because it presents just the right amount of information, just the right way. Edited by the late Thomas E. Andreoli, MD as well as Ivor Benjamin, MD, Robert C. Griggs, MD, and Edward J. Wing, MD, it focuses on core principles and how they apply to patient care, covering everything you need to know to succeed on a medical rotation or residency. Masterful editing and a user-friendly full-color design make absorbing and retaining information as effortless as possible. New chapters on "Pre- and Post-Operative Care" and "Palliative Care," plus the integration of molecular biology and other new horizons in medicine, familiarize you with the most current clinical concepts. An expanded International Editorial Board provides increased input from respected practitioners worldwide. Excellent images and clinical photographs vividly illustrate the appearance and clinical features of disease. Masterful editing and a user-friendly full-color design make absorbing and retaining information as effortless as possible.

Textbook Of Pediatric Rheumatology E Book

Author: James T. Cassidy
Publisher: Elsevier Health Sciences
ISBN: 1437735967
Size: 23.22 MB
Format: PDF, Mobi
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Textbook of Pediatric Rheumatology examines the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents, detailing the presentation, differential diagnosis, course, management, and prognosis of every major condition. Drs. James T. Cassidy, Ross E. Petty, Ronald M. Laxer, and Carol B. Lindsley discuss recent developments in diagnosis, treatment, genetics, immunology, imaging, and more. Diagnose and treat effectively through exhaustive reviews of the complex symptoms and signs and lab abnormalities that characterize these clinical disorders. Choose treatment protocols based on the best scientific evidence available today. Apply the knowledge and experience of the leading experts in the field. Keep current with coverage of new topics including macrophage activation syndrome, pediatric sarcoidosis, uveitis, imaging, and occupational and physical therapy. Tap into detailed discussions of recent advances in the field, new research on the immunologic mechanisms of inflammatory disease, and new developments on biologic treatments for arthritis in ten new chapters. Master complex concepts and key techniques with a full-color design and full-color illustrations.

Allergy E Book

Author: Stephen T Holgate
Publisher: Elsevier Health Sciences
ISBN: 0702050415
Size: 68.11 MB
Format: PDF, ePub, Docs
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The new edition of Allergy, by Drs. Stephen Holgate, Martin Church, David Broide, and Fernando Martinez, uses an enhanced clinical focus to provide the clear, accessible guidance you need to treat allergy patients. A more consistent format throughout features new differential diagnosis and treatment algorithms, updated therapeutic drug information in each chapter, and additional coverage of pediatric allergies. With current discussions of asthma, allergens, pollutants, drug treatment, and more, this comprehensive resource is ideal for any non-specialist who treats patients with allergies. Prescribe appropriate therapies and effectively manage patients’ allergies using detailed treatment protocols. Identify allergic conditions quickly and easily with algorithms that provide at-a-glance assistance. Explore topics in greater detail using extensive references to key literature. Manage allergies in both adult and pediatric patients using coverage of treatment practices for both in each chapter. Stay current on hot topics including asthma, allergens, pollutants, and more. Get up-to-date coverage of cell-based condition with brand new chapters on Eosinophilia: Clinical Manifestations and Therapeutic Options and Systemic Mastocytosis. Apply the latest best practices through new and updated treatment algorithms. Find therapeutic drug information more easily with guidance incorporated into each chapter.

Oxidative Phosphorylation In Health And Disease

Author: Jan A.M. Smeitink
Publisher: Springer Science & Business Media
ISBN: 9780306482328
Size: 26.96 MB
Format: PDF
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Mitochondrial diseases are often hard to diagnose. From the time they were first researched without animal models, patients of mitochondrial diseases were of equal interest to both clinical and basic scientists. With the new research done, this book includes updates on the normal structure, function, and molecular biology of the mitochondrial respiratory chain, information on traditional diagnostical methodologies, and an overview of the diagnostic promise of new technologies. The hypermetabolism of Luft disease, although only seen twice, is also studied. There are critical reviews of symptoms and signs associated with syndromes, as well as updates on the genetic defects of either the mitochondrial or the nuclear genome responsible for many disorders.