Guidelines For Process Safety In Bioprocess Manufacturing Facilities

Author: CCPS (Center for Chemical Process Safety)
Publisher: John Wiley & Sons
ISBN: 1118009002
Size: 79.62 MB
Format: PDF
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This book helps advance process safety in a key area of interest. Currently, no literature exists which is solely dedicated to process safety for the bioprocessing industry. There are texts, guidelines, and standards on biosafety at the laboratory level and for industrial hygiene, but no guidelines for large-scale production facilities. In fact, biosafety is largely defined as a field that promotes safe laboratory practices, procedures and use of containment equipment and facilities. Additionally, biomedical engineers, biologists, or other professionals without chemical engineering training or knowledge of inherently safe design are designing many of these facilities.

Guidelines For Risk Based Process Safety

Author: Center for Chemical Process Safety (CCPS)
Publisher: John Wiley & Sons
ISBN: 0470165693
Size: 37.49 MB
Format: PDF, Mobi
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Guidelines for Risk Based Process Safety provides guidelines for industries that manufacture, consume, or handle chemicals, by focusing on new ways to design, correct, or improve process safety management practices. This new framework for thinking about process safety builds upon the original process safety management ideas published in the early 1990s, integrates industry lessons learned over the intervening years, utilizes applicable "total quality" principles (i.e., plan, do, check, act), and organizes it in a way that will be useful to all organizations - even those with relatively lower hazard activities - throughout the life-cycle of a company.

Canadian Biosafety Standards And Guidelines For Facilities Handling Human And Terrestrial Animal Pathogens Prions And Biological Toxins

Author: Public Health Agency of Canada
Publisher: Canadian Museum of Civilization/Musee Canadien Des Civilisations
ISBN:
Size: 63.32 MB
Format: PDF
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This first edition of the Canadian Biosafety Standards and Guidelines (CBSG) is a harmonized national standard for the handling and storing of human and terrestrial animal pathogens and toxins in Canada. The CBSG is the result of a joint initiative undertaken by the Public Health Agency of Canada (PHAC) and the Canadian Food Inspection Agency (CFIA) to update and harmonize existing Canadian biosafety standards and guidelines. It is intended to facilitate compliance by incorporating risk-, evidence- and, where possible, performance-based biosafety and biosecurity requirements, and by streamlining the requirements for handling or storing human or terrestrial animal pathogens and toxins into a single national reference document.

Biopharmaceutical Processing

Author: Gunter Jagschies
Publisher: Elsevier
ISBN: 0128125527
Size: 80.97 MB
Format: PDF
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Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing Processes covers bioprocessing from cell line development to bulk drug substances. The methods and strategies described are essential learning for every scientist, engineer or manager in the biopharmaceutical and vaccines industry. The integrity of the bioprocess ultimately determines the quality of the product in the biotherapeutics arena, and this book covers every stage including all technologies related to downstream purification and upstream processing fields. Economic considerations are included throughout, with recommendations for lowering costs and improving efficiencies. Designed for quick reference and easy accessibility of facts, calculations and guidelines, this book is an essential tool for industrial scientists and managers in the biopharmaceutical industry. Offers a comprehensive, go-to reference for daily work decisions Covers both upstream and downstream processes Includes case studies that emphasize financial outcomes Presents summaries, decision grids, graphs and overviews for quick reference

Process Architecture In Biomanufacturing Facility Design

Author: Jeffery Odum
Publisher: John Wiley & Sons
ISBN: 1118833651
Size: 65.89 MB
Format: PDF, ePub
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Essential information for architects, designers, engineers, equipment suppliers, and other professionals who are working in or entering the biopharmaceutical manufacturing field Biomanufacturing facilities that are designed and built today are radically different than in the past. The vital information and knowledge needed to design and construct these increasingly sophisticated biopharmaceutical manufacturing facilities is difficult to find in published literature—and it’s rarely taught in architecture or design schools. This is the first book for architects and designers that fills this void. Process Architecture in Biomanufacturing Facility Design provides information on design principles of biopharmaceutical manufacturing facilities that support emerging innovative processes and technologies, use state-of-the-art equipment, are energy efficient and sustainable, and meet regulatory requirements. Relying on their many years of hands-on design and operations experience, the authors emphasize concepts and practical approaches toward design, construction, and operation of biomanufacturing facilities, including product-process-facility relationships, closed systems and single use equipment, aseptic manufacturing considerations, design of biocontainment facility and process based laboratory, and sustainability considerations, as well as an outlook on the facility of the future. Provides guidelines for meeting licensing and regulatory requirements for biomanufacturing facilities in the U.S.A and WHO—especially in emerging global markets in India, China, Latin America, and the Asia/Pacific regions Focuses on innovative design and equipment, to speed construction and time to market, increase energy efficiency, and reduce footprint, construction and operational costs, as well as the financial risks associated with construction of a new facility prior to the approval of the manufactured products by regulatory agencies Includes many diagrams that clarify the design approach Process Architecture in Biomanufacturing Facility Design is an ideal text for professionals involved in the design of facilities for manufacturing of biopharmaceuticals and vaccines, biotechnology, and life-science industry, including architects and designers of industrial facilities, construction, equipment vendors, and mechanical engineers. It is also recommended for university instructors, advanced undergraduates, and graduate students in architecture, industrial engineering, mechanical engineering, industrial design, and industrial interior design.

Bioprocessing Safety

Author: Warren C. Hyer
Publisher: ASTM International
ISBN: 9780803112643
Size: 22.57 MB
Format: PDF, ePub, Mobi
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Process Plant Equipment

Author: Michael D. Holloway
Publisher: John Wiley & Sons
ISBN: 1118162544
Size: 60.20 MB
Format: PDF, Kindle
View: 6110
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“Process Plant Equipment Book is another great publication from Wiley as a reference book for final year students as well as those who will work or are working in chemical production plants and refinery…” -Associate Prof. Dr. Ramli Mat, Deputy Dean (Academic), Faculty of Chemical Engineering, Universiti Teknologi Malaysia “…give[s] readers access to both fundamental information on process plant equipment and to practical ideas, best practices and experiences of highly successful engineers from around the world… The book is illustrated throughout with numerous black & white photos and diagrams and also contains case studies demonstrating how actual process plants have implemented the tools and techniques discussed in the book. An extensive list of references enables readers to explore each individual topic in greater depth…” –Stainless Steel World and Valve World, November 2012 Discover how to optimize process plant equipment, from selection to operation to troubleshooting From energy to pharmaceuticals to food, the world depends on processing plants to manufacture the products that enable people to survive and flourish. With this book as their guide, readers have the information and practical guidelines needed to select, operate, maintain, control, and troubleshoot process plant equipment so that it is efficient, cost-effective, and reliable throughout its lifetime. Following the authors' careful explanations and instructions, readers will find that they are better able to reduce downtime and unscheduled shutdowns, streamline operations, and maximize the service life of processing equipment. Process Plant Equipment: Operation, Control, and Reliability is divided into three sections: Section One: Process Equipment Operations covers such key equipment as valves, pumps, cooling towers, conveyors, and storage tanks Section Two: Process Plant Reliability sets forth a variety of tested and proven tools and methods to assess and ensure the reliability and mechanical integrity of process equipment, including failure analysis, Fitness-for-Service assessment, engineering economics for chemical processes, and process component function and performance criteria Section Three: Process Measurement, Control, and Modeling examines flow meters, process control, and process modeling and simulation Throughout the book, numerous photos and diagrams illustrate the operation and control of key process equipment. There are also case studies demonstrating how actual process plants have implemented the tools and techniques discussed in the book. At the end of each chapter, an extensive list of references enables readers to explore each individual topic in greater depth. In summary, this text offers students, process engineers, and plant managers the expertise and technical support needed to streamline and optimize the operation of process plant equipment, from its initial selection to operations to troubleshooting.

Chemical Engineering Design

Author: Gavin P. Towler
Publisher: Butterworth-Heinemann
ISBN:
Size: 14.88 MB
Format: PDF, Mobi
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"Bottom line: For a holistic view of chemical engineering design, this book provides as much, if not more, than any other book available on the topic." --Extract from Chemical Engineering Resources review. Chemical Engineering Design is one of the best-known and widely adopted texts available for students of chemical engineering. It deals with the application of chemical engineering principles to the design of chemical processes and equipment. Revised throughout, this US edition has been specifically developed for the US market. It covers the latest aspects of process design, operations, safety, loss prevention and equipment selection, among others. Comprehensive in coverage, exhaustive in detail, it is supported by extensive problems and a separate solutions manual for adopting tutors and lecturers. In addition, the book is widely used by professions as a day-to-day reference.

Introduction To Process Safety For Undergraduates And Engineers

Author: CCPS (Center for Chemical Process Safety)
Publisher: John Wiley & Sons
ISBN:
Size: 55.97 MB
Format: PDF, Kindle
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This book introduces the reader with the need for process safety. It focuses on topics of various engineering disciplines; introduces the student to the 20 elements of process safety defined by the CCPS; provides case histories of 16 process safety incidents and how management systems failures contributed to them, gives examples of process safety in design, and shows how the various of aspects of process safety have a direct tie-in to existing chemical engineering curricula.