Genomics Circuits And Pathways In Clinical Neuropsychiatry

Author: Thomas Lehner
Publisher: Academic Press
ISBN: 0128005300
Size: 34.17 MB
Format: PDF
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This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders. Provides interdisciplinary appeal in psychiatry, neurology, neuroscience, and genetics Identifies key concepts, methods, and findings Includes coverage of multiple disorders from autism to schizophrenia Reviews specific genes associated with disorders Discusses the genetic architecture of these syndromes Explains how recent findings are influencing the understanding of biology Clarifies the promise of these findings for future treatment

The Autisms

Author: Mary Coleman
Publisher: OUP USA
ISBN: 0199732124
Size: 42.34 MB
Format: PDF, Mobi
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Rev. ed. of: Biology of the autistic syndromes / Christopher Gillberg, Mary Coleman. 3rd ed. 2000.

Optogenetics

Author: Krishnarao Appasani
Publisher: Cambridge University Press
ISBN: 1107053013
Size: 67.15 MB
Format: PDF
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Discovered little more than a decade ago, optogenetics - a revolutionary technique combining genetic and optical methods to observe and control the function of neurons - is now a widely used research tool. Optogenetics-driven research has led to insights into Parkinson's disease and other neurological and psychiatric disorders. With contributions from leaders and innovators from both academia and industry, this volume explores the discovery and application of optogenetics, from the basic science to its potential clinical use. Chapters cover a range of optogenetics applications, including for brain circuits, plasticity, memory, learning, sleep, vision and neurodegenerative and neuropsychiatric diseases. Providing authoritative coverage of the huge potential that optogenetics research carries, this is an ideal resource for researchers and graduate students, as well as for those working in the biotechnology and pharmaceutical industries and in a clinical setting.

Molecular Neuropharmacology

Author: Eric J. Nestler
Publisher: McGraw Hill Professional
ISBN: 9780071641197
Size: 32.24 MB
Format: PDF, Mobi
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Market: Pharmacy and medical students; neuroscientists; neurologists; pharmacologists Updated edition has an attractive full-color design with more illustrations Includes numerous Fact Boxes to help reinforce learning

Anatomy Of Delusion

Author: Henry Kellerman
Publisher: Lantern Books
ISBN: 1590564332
Size: 11.93 MB
Format: PDF, ePub, Mobi
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There exist a plethora of definitions to the concept of delusion. Some are quite general, some more specific, and some more in-depth. Yet, it is accepted that preventing or curing delusional thinking has not yet acquired a tactical procedure or approach. Ostensibly, this means that the essence of any bona fide delusion is simply not understood by the vast majority of theoretical and/or practicing clinicians. Historically, it means that the trigger, the motive, and the psychic arrangement of forces of the phenomenon defined as delusion have been elusive. Dr. Kellerman, the author of Personality: How it Forms, brings the problem of delusion into sharper focus for a better understanding.

Basics Of Anesthesia 6 E

Author: Ronald D. Miller
Publisher: Elsevier India
ISBN: 8131228983
Size: 49.61 MB
Format: PDF
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With the most authoritative and complete overview of anesthesia theory and practice, the latest edition of Basic Anesthesia, edited by noted anesthesiologist Ronald D. Miller, MD and Manuel C. Pardo, Jr., MD, continues to serve as an excellent primer on the scope and practice of anesthesiology. Widely acknowledged as the foremost introductory text, the new edition-now presented in full color throughout-has been thoroughly updated to reflect new and rapidly changing areas in anesthesia practice including new chapters on awareness under anesthesia, quality and patient safety, orthopedics, and expanded coverage of new ultrasound techniques in regional anesthesiology with detailed illustrated guidance. You can access the full text and image library online at www.expertconsult.com. Obtain a clear overview of everything you need to know about the fundamentals of anesthesia, including basic science and emerging clinical topics. Efficiently retain and synthesize information more easily thanks to a concise, at-a-glance format with numerous illustrations and tables throughout the book that condense complex concepts, and 'Questions of the Day' to assist you in understanding key material presented in each chapter.

Movement Disorders

Author: Mark S. LeDoux
Publisher: Elsevier
ISBN: 9780080470566
Size: 20.94 MB
Format: PDF, Kindle
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The use of animal models is a key aspect of scientific research in numerous fields of medicine. This book vigorously examines the important contributions and application of animal models to the understanding of human movement disorders and will serve as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. A vital feature of this book is an accompanying DVD with video clips of human movement disorders and their corresponding animal models. The book is divided into sections on Parkinson disease, Huntington disease, dystonia, tremor, paroxysmal movement disorders, ataxia, myoclonus, restless legs syndrome, drug-induced movement disorders, multiple system atrophy, progressive supranuclear palsy/corticobasal degeneration and spasticity. This book serves as an essential resource for both clinicians interested in the science being generated with animal models and basic scientists studying the pathogenesis of particular movement disorders. * Provides a single comprehensive resource on animal models of movement disorders that academic clinicians, translational researchers, and basic neuroscientists can refer to * Includes contributions by expert movement disorder clinicians and top-level researchers in the field * Features a DVD containing over 170 video clips of human movement disorders and the corresponding animal models

Fundamental Neuroscience

Author: Larry R. Squire
Publisher: Academic Press
ISBN: 0123858704
Size: 22.19 MB
Format: PDF, ePub
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Fundamental Neuroscience, 3rd Edition introduces graduate and upper-level undergraduate students to the full range of contemporary neuroscience. Addressing instructor and student feedback on the previous edition, all of the chapters are rewritten to make this book more concise and student-friendly than ever before. Each chapter is once again heavily illustrated and provides clinical boxes describing experiments, disorders, and methodological approaches and concepts. A companion web site contains test questions, and an imagebank of the figures for ready use in presentations, slides, and handouts. Capturing the promise and excitement of this fast-moving field, Fundamental Neuroscience, 3rd Edition is the text that students will be able to reference throughout their neuroscience careers! New to this edition: * 30% new material including new chapters on Dendritic Development and Spine Morphogenesis, Chemical Senses, Cerebellum, Eye Movements, Circadian Timing, Sleep and Dreaming, and Consciousness * Companion website with figures, web links to additional material, and test questions * Additional text boxes describing key experiments, disorders, methods, and concepts * Multiple model system coverage beyond rats, mice, and monkeys * Extensively expanded index for easier referencing

The Prescriber S Guide Antidepressants

Author: Stephen M. Stahl
Publisher: Cambridge University Press
ISBN: 1107667968
Size: 17.30 MB
Format: PDF, Docs
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This spin-off from Stephen Stahl's new, completely revised, and fully updated fourth edition of the Prescriber's Guide covers the most important drugs in use today for treating depression. Now established as the indispensable formulary in psychopharmacology, easy to navigate and easy to use, the Prescriber's Guide combines evidence-based information with clinically-informed guidance to support clinicians in making the most effective prescribing decisions for the good of their patients. Incorporating information on the newest indications, new formulations, new recommendations and new safety data, this edition continues to provide the essential practical support required by anyone prescribing in the field of mental health.