Essentials Of In Vivo Biomedical Imaging

Author: Simon R. Cherry
Publisher: CRC Press
ISBN: 1439898758
Size: 67.94 MB
Format: PDF
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While there are many excellent texts focused on clinical medical imaging, there are few books that approach in vivo imaging technologies from the perspective of a scientist or physician–scientist using, or interested in using, these techniques in research. It is for these individuals that Essentials of In Vivo Biomedical Imaging is written. Featuring contributions from leading experts in the field, this authoritative reference text helps answer the following often-asked questions: Can imaging address my question? Which technique should I use? How does it work? What information does it provide? What are its strengths and limitations? What applications is it best suited for? How can I analyze the data? By explaining what each imaging technology can measure, describing major methods and approaches, and giving examples demonstrating the rich repertoire of modern biomedical imaging to address a wide range of morphological, functional, metabolic, and molecular parameters in a safe and noninvasive manner, Essentials of In Vivo Biomedical Imaging helps scientists and physician–scientists choose and utilize the appropriate in vivo imaging technologies and methods for their research.

Small Animal Imaging

Author: Fabian Kiessling
Publisher: Springer
ISBN: 3319422022
Size: 11.69 MB
Format: PDF, ePub, Mobi
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This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, and applications. Additional useful hints are also supplied on the installation of a small animal unit, study planning, animal handling, and cost-effective performance of small animal imaging. Cross-calibration methods and data postprocessing are considered in depth. This new edition of Small Animal Imaging will be an invaluable aid for researchers, students, and technicians involved in research into and applications of small animal imaging.

Biomedical Imaging In Experimental Neuroscience

Author: Nick Van Bruggen
Publisher: CRC Press
ISBN: 1420042157
Size: 25.51 MB
Format: PDF, Kindle
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Recent years have seen an explosion of activity in the field of biomedical imaging in an attempt to understand the behavior of the brain in healthy and disease states. With the emergence of genetically manipulated laboratory mice and the knowledge of the mouse genome, we are entering an exciting new era with revolutionary tools for experimental research. Noninvasive imaging techniques capable of providing both anatomical and functional descriptions of the brain have become essential. Among the various imaging methodologies, magnetic resonance imaging (MRI) stands in the forefront by virtue of its contrast versatility and pathophysiological specificity. Emphasizing the relationship between physiological microenvironment and macroscopic imaging signal changes, Biomedical Imaging in Experimental Neuroscience presents a comprehensive review of the noninvasive biomedical imaging techniques available for laboratory animal research. Focusing on MRI, but recognizing the multiple forms of imaging information, this book outlines the scope and limitations of these methods and analyzes their impact on in vivo neuroscience research. The book is intended for the biologist who may not have a background in the physical sciences. This applied guide also provides a concise theoretical description of the pertinent physics. Noninvasive imaging offers the obvious benefits of reducing sample sizes and identifying new and unanticipated behaviors. Biomedical Imaging in Experimental Neuroscience presents detailed information for biologists interested in how biomedical imaging may augment their in vivo research and for clinical practitioners seeking deeper insights into the association between imaging findings and disease pathophysiology.

Nanobiomaterials In Medical Imaging

Author: Alexandru Grumezescu
Publisher: William Andrew
ISBN: 0323417388
Size: 61.91 MB
Format: PDF
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Nanobiomaterials in Medical Imaging presents the latest developments in medical exploratory approaches using nanotechnology. Leading researchers from around the world discuss recent progress and state-of-the-art techniques. The book covers synthesis and surface modification of multimodal imaging agents, popular examples of nanoparticles and their applications in different imaging techniques, and combinatorial therapy for the development of multifunctional nanocarriers. The advantages and potential of current techniques are also considered. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians. A valuable resource for researchers, practitioners and students working in biomedical, biotechnological and engineering fields A detailed guide to recent scientific progress, along with the latest application methods Presents innovative opportunities and ideas for developing or improving technologies in nanomedicine and medical imaging

Introduction To The Science Of Medical Imaging

Author: R. Nick Bryan
Publisher: Cambridge University Press
ISBN: 0521747627
Size: 35.24 MB
Format: PDF, Docs
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This landmark text from world-leading radiologist describes and illustrates how imaging techniques are created, analyzed and applied to biomedical problems.

The Transparent Body

Author: Jose Van Dijck
Publisher: University of Washington Press
ISBN: 029599035X
Size: 51.75 MB
Format: PDF, ePub
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From the potent properties of X rays evoked in Thomas Mann's Magic Mountain to the miniaturized surgical team of the classic science fiction film Fantastic Voyage, the possibility of peering into the inner reaches of the body has engaged the twentieth-century popular and scientific imagination. Drawing on examples that are international in scope, The Transparent Body examines the dissemination of medical images to a popular audience, advancing the argument that medical imaging technologies are the material embodiment of collective desires and fantasies--the most pervasive of which is the ideal of transparency itself. The Transparent Body traces the cultural context and wider social impact of such medical imaging practices as X ray and endoscopy, ultrasound imaging of fetuses, the filming and broadcasting of surgical operations, the creation of plastinated corpses for display as art objects, and the use of digitized cadavers in anatomical study. In the early twenty-first century, the interior of the body has become a pervasive cultural presence - as accessible to the public eye as to the physician's gaze. Jose van Dijck explores the multifaceted interactions between medical images and cultural ideologies that have brought about this situation. The Transparent Body unfolds the complexities involved in medical images and their making, illuminating their uses and meanings both within and outside of medicine. Van Dijck demonstrates the ways in which the ability to render the inner regions of the human body visible - and the proliferation of images of the body's interior in popular media - affect our view of corporeality and our understanding of health and disease. Written in an engaging style that brings thought-provoking cultural intersections vividly to life, The Transparent Body will be of special interest to those in media studies, cultural studies, science and technology studies, medical humanities, and the history of medicine.

Biomedical Image Quantification Of Preclinical In Vivo Studies Evaluating The Accuracy Of Different Software Specific Roi Voi Delineation Tools

Author: Marko Djerkovic
Publisher:
ISBN:
Size: 77.30 MB
Format: PDF, ePub, Docs
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Over the past few years in-vivo multimodal preclinical imaging has become an essential tool in small animal research presenting the opportunity to observe physiological and morphological changes in living organisms at a molecular level. Hence, by the use of imaging modalities such as μPET/CT scanners biologic functions can be explored providing direct information about the spatial distribution of certain biologic processes. To exploit this wealth of information with regard to pharmacokinetics, it is necessary to localize all relevant tissue structures and assess their tracer concentration. Manual segmentation is a tedious process and thus prone to considerable interobserver variability resulting in a direct impact on the delineation accuracy. Therefore, the focus of this thesis is to take a close look at co-registered μPET/CT images of mice and to establish a semi-automated workflow allowingaccurate delineation of volumes of interest in a reproducible way using two different VOI quantification software packages. These are into relation and evaluated in regard to their highest accuracy, reliability and reproducibility.Keywords : Preclinical, μPET image, ROI, VOI, delineation, region, SUV value, radiotracer, information, quantification, statistical, software.*****Over the past few years in-vivo multimodal preclinical imaging has become an essential tool in small animal research presenting the opportunity to observe physiological and morphological changes in living organisms at a molecular level. Hence, by the use of imaging modalities such as μPET/CT scanners biologic functions can be explored providing direct information about the spatial distribution of certain biologic processes. To exploit this wealth of information with regard to pharmacokinetics, it is necessary to localize all relevant tissue structures and assess their tracer concentration. Manual segmentation is a tedious process and thus prone to considerable interobserver variability resulting in a direct impact on the delineation accuracy. Therefore, the focus of this thesis is to take a close look at co-registered μPET/CT images of mice and to establish a semi-automated workflow allowingaccurate delineation of volumes of interest in a reproducible way using two different VOI quantification software packages. These are into relation and evaluated in regard to their highest accuracy, reliability and reproducibility.Keywords : Preclinical, μPET image, ROI, VOI, delineation, region, SUV value, radiotracer, information, quantification, statistical, software.

Iron Oxide Nanoparticles For Biomedical Applications

Author: Sophie Laurent
Publisher: Elsevier
ISBN: 0081012756
Size: 55.83 MB
Format: PDF, ePub
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Iron Oxide Nanoparticles for Biomedical Applications: Synthesis, Functionalization and Application begins with several chapters covering the synthesis, stabilization, physico-chemical characterization and functionalization of iron oxide nanoparticles. The second part of the book outlines the various biomedical imaging applications that currently take advantage of the magnetic properties of iron oxide nanoparticles. Brief attention is given to potential iron oxide based therapies, while the final chapter covers nanocytotoxicity, which is a key concern wherever exposure to nanomaterials might occur. This comprehensive book is an essential reference for all those academics and professionals who require thorough knowledge of recent and future developments in the role of iron oxide nanoparticles in biomedicine. Unlocks the potential of iron oxide nanoparticles to transform diagnostic imaging techniques Contains full coverage of new developments and recent research, making this essential reading for researchers and engineers alike Explains the synthesis, processing and characterization of iron oxide nanoparticles with a view to their use in biomedicine

Monitoring And Evaluation Of Biomaterials And Their Performance In Vivo

Author: Roger Narayan
Publisher: Woodhead Publishing
ISBN: 0081006047
Size: 50.98 MB
Format: PDF
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Monitoring and Evaluation of Biomaterials and Their Performance In Vivo provides essential information for scientists and researchers who need to assess and evaluate performance, monitor biological responses, gauge efficacy, and observe changes over time. Crucially, it also enables the optimization of design for future biomaterials and implants. This book presents readers with comprehensive coverage of the topic of in vivo monitoring of medical implants and biomaterials. Contains a specific focus on monitoring and evaluation of biomaterials in vivo Multi-faceted coverage of materials function and performance Focuses on a range of implants and subsequent bodily reactions

Introduction To Subsurface Imaging

Author: Bahaa Saleh
Publisher: Cambridge University Press
ISBN: 1139495348
Size: 54.35 MB
Format: PDF
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Describing and evaluating the basic principles and methods of subsurface sensing and imaging, Introduction to Subsurface Imaging is a clear and comprehensive treatment that links theory to a wide range of real-world applications in medicine, biology, security and geophysical/environmental exploration. It integrates the different sensing techniques (acoustic, electric, electromagnetic, optical, x-ray or particle beams) by unifying the underlying physical and mathematical similarities, and computational and algorithmic methods. Time-domain, spectral and multisensor methods are also covered, whilst all the necessary mathematical, statistical and linear systems tools are given in useful appendices to make the book self-contained. Featuring a logical blend of theory and applications, a wealth of color illustrations, homework problems and numerous case studies, this is suitable for use as both a course text and as a professional reference.