Elizabeth Blackburn And The Story Of Telomeres

Author: Catherine Brady
Publisher: MIT Press
ISBN: 0262261960
Size: 10.53 MB
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Molecular biologist Elizabeth Blackburn -- one of Time magazine's 100 "Most Influential People in the World" in 2007 -- made headlines in 2004 when she was dismissed from the President's Council on Bioethics after objecting to the council's call for a moratorium on stem cell research and protesting the suppression of relevant scientific evidence in its final report. But it is Blackburn's groundbreaking work on telomeric DNA, which launched the field of telomere research, that will have the more profound and long-lasting effect on science and society. In this compelling biography, Catherine Brady tells the story of Elizabeth Blackburn's life and work and the emergence of a new field of scientific research on the specialized ends of chromosomes and the enzyme, telomerase, that extends them. In the early stages of telomere research, telomerase, heralded as a potential cure for cancer and diseases related to aging, attracted the voracious interest of biotech companies. The surrounding hype succeeded in confusing the role of telemorase in extending the life of a cell with a mechanism that might extend the lifespan of an entire organism. In Brady's hands, Blackburn's story reveals much about the tension between pure and applied science, the politicking that makes research science such a competitive field, and the resourceful opportunism that characterizes the best scientific thinking. Brady describes the science accessibly and compellingly. She explores Blackburn's struggle to break down barriers in an elite, male-dominated profession, her role as a mentor to other women scientists (many of whom have made their mark in telomere research), and the collaborative nature of scientific work. This book gives us a vivid portrait of an exceptional woman and a new understanding of the combination of curiosity, imaginative speculation, and aesthetic delight that powers scientific discovery.Catherine Brady is Assistant Professor in the MFA in Writing Program at the University of San Francisco. She is the author of two collections of short stories, The End of the Class War and Curled in the Bed of Love (a winner of the 2002 Flannery O'Connor Award for Short Fiction).

It S In Your Dna

Author: Eugene Rosenberg
Publisher: Academic Press
ISBN: 0128125683
Size: 32.14 MB
Format: PDF
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It's in Your DNA: From Discovery to Structure, Function and Role in Evolution, Cancer and Aging describes, in a clear, approachable manner, the progression of the experiments that eventually led to our current understanding of DNA. This fascinating work tells the whole story from the discovery of DNA and its structure, how it replicates, codes for proteins, and our current ability to analyze and manipulate it in genetic engineering to begin to understand the central role of DNA in evolution, cancer, and aging. While telling the scientific story of DNA, this captivating treatise is further enhanced by brief sketches of the colorful lives and personalities of the key scientists and pioneers of DNA research. Major discoveries by Meischer, Darwin, and Mendel and their impacts are discussed, including the merging of the disciplines of genetics, evolutionary biology, and nucleic acid biochemistry, giving rise to molecular genetics. After tracing development of the gene concept, critical experiments are described and a new biological paradigm, the hologenome concept of evolution, is introduced and described. The final two chapters of the work focus on DNA as it relates to cancer and gerontology. This book provides readers with much-needed knowledge to help advance their understanding of the subject and stimulate further research. It will appeal to researchers, students, and others with diverse backgrounds within or beyond the life sciences, including those in biochemistry, genetics/molecular genetics, evolutionary biology, epidemiology, oncology, gerontology, cell biology, microbiology, and anyone interested in these mechanisms in life. Highlights the importance of DNA research to science and medicine Explains in a simple but scientifically correct manner the key experiments and concepts that led to the current knowledge of what DNA is, how it works, and the increasing impact it has on our lives Emphasizes the observations and reasoning behind each novel idea and the critical experiments that were performed to test them

The Vaccine Race

Author: Meredith Wadman
Publisher: Penguin
ISBN: 0525427538
Size: 34.70 MB
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"The rubella vaccine and others made with ... fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles, and adenovirus. Meredith Wadman's [book] covers not only the science of this [advancement], but also the political roadblocks that nearly stopped the scientists"--Provided by publisher.

Imperfect Oracle

Author: Theodore L. Brown
Publisher: Penn State Press
ISBN: 0271046295
Size: 22.60 MB
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Science and its offshoot, technology, enter into the very fabric of our society in so many ways that we cannot imagine life without them. We are surrounded by crises and debates over climate change, stem-cell research, AIDS, evolutionary theory and &“intelligent design,&” the use of DNA in solving crimes, and many other issues. Society is virtually forced to follow our natural tendency, which is to give great weight to the opinions of scientific experts. How is it that these experts have come to acquire such authority, and just how far does their authority reach? Does specialized knowledge entitle scientists to moral authority as well? How does scientific authority actually function in our society, and what are the countervailing social forces (including those deriving from law, politics, and religion) with which it has to contend? Theodore Brown seeks to answer such questions in this magisterial work of synthesis about the role of science in society. In Part I, he elucidates the concept of authority and its relation to autonomy, and then traces the historical growth of scientific authority and its place in contemporary American society. In Part II, he analyzes how scientific authority plays out in relation to other social domains, such as law, religion, government, and the public sphere.

Curled In The Bed Of Love

Author: Catherine Brady
Publisher: University of Georgia Press
ISBN: 9780820325453
Size: 49.27 MB
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Eleven stories chronicle the lives of characters who avoid middle class lifestyles while clinging to their youthful idealisms, including Jim and his AIDS-afflicted partner, and a woman who confesses to an affair with her cousin's fiancâe.

The Telomere Effect

Author: Dr. Elizabeth Blackburn
Publisher: Grand Central Publishing
ISBN: 1455587966
Size: 40.92 MB
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NEW YORK TIMES BESTSELLER The revolutionary book coauthored by the Nobel Prize winner who discovered telomerase and telomeres' role in the aging process and the health psychologist who has done original research into how specific lifestyle and psychological habits can protect telomeres, slowing disease and improving life. Have you wondered why some sixty-year-olds look and feel like forty-year-olds and why some forty-year-olds look and feel like sixty-year-olds? While many factors contribute to aging and illness, Dr. Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection. They and other scientists have found that changes we can make to our daily habits can protect our telomeres and increase our health spans (the number of years we remain healthy, active, and disease-free). THE TELOMERE EFFECT reveals how Blackburn and Epel's findings, together with research from colleagues around the world, cumulatively show that sleep quality, exercise, aspects of diet, and even certain chemicals profoundly affect our telomeres, and that chronic stress, negative thoughts, strained relationships, and even the wrong neighborhoods can eat away at them. Drawing from this scientific body of knowledge, they share lists of foods and suggest amounts and types of exercise that are healthy for our telomeres, mind tricks you can use to protect yourself from stress, and information about how to protect your children against developing shorter telomeres, from pregnancy through adolescence. And they describe how we can improve our health spans at the community level, with neighborhoods characterized by trust, green spaces, and safe streets. THE TELOMERE EFFECT will make you reassess how you live your life on a day-to-day basis. It is the first book to explain how we age at a cellular level and how we can make simple changes to keep our chromosomes and cells healthy, allowing us to stay disease-free longer and live more vital and meaningful lives.

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Size: 41.67 MB
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The End Of The Class War

Author: Catherine Brady
Publisher: CALYX Books
ISBN: 9780934971676
Size: 79.78 MB
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Short Fiction. In the noisy, crowded kitchens of [Catherine Brady's] working-class Irish American households, proud, strong willed articulate women contend with the challenges of lonliness, poverty, and disabling illness. Blessed -- and cursed -- with a predisposition toward caring for others, Ms. Brady's heroines have an instinctive compassion for the fragile and the needy. They draw strength from their faith and their families to resist despair -- Jennifer C. Cornell). The little girls tumble on the lawn in their pajamas, their damp hair curled in ringlets their mother has carefully shaped around her finger before she let them out into the warm summer night. The girls do cartwheels, somersalts, wobbly headstands. They're a oneness, a jumble of seal-smooth, perfect bodies, sleek bellies bared when they reach their arms, lovely arched feet, firm rumps that could be cupped in two hands. Hiding from the camera, their mother crouches beside their aunt and uncle in their lawn chairs, plump and squat, her body an impossible o

Biology Today And Tomorrow With Physiology

Author: Cecie Starr
Publisher: Cengage Learning
ISBN: 0495016543
Size: 49.34 MB
Format: PDF, ePub, Docs
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Cecie Starr is the most successful author in non-majors biology because of her clear and engaging writing, trend-setting art, and unparalleled media. BIOLOGY TODAY AND TOMORROW, her most concise text, provides a precise, issues-oriented approach and solves some of the toughest course challenges: engaging students, linking concepts from chapter to chapter, easily monitoring students' progress and simplifying lecture prep. Show students how biology matters: opening each chapter with engaging essays on hot issues and related online voting, the text highlights the connections between biology and real-life. Online exercises promote critical thinking about issues students will face as consumers, parents and citizens. Link concepts from chapter to chapter: since students have a difficult time linking concepts, the authors created a new linking tool. A list at the start of each chapter reminds students of related topics that were explained earlier. Within chapters, a key icon identifies cross-references to relevant sections in earlier chapters. As students work through the text, they see how topics build upon one another. Monitor students' progress with ease: BiologyNowTM offers diagnostic quizzes with automatically graded results that flow directly into your instructor grade book (iLrn, WebCT or BlackBoard). And, to assess students' progress instantly with in-class quizzes and polls, you can use JoinIn on TurningPoint content and software. Enjoy easier lecture prep: The new PowerLecture tool integrates all electronic chapter assets - art, photos, animations, videos, links to InfoTrac articles, web links, bulleted text slides, and everything else you need into each chapter's lecture slides. This buffet of media resources-arranged by chapter section-is at your fingertips. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.

Fundamental Molecular Biology 2nd Edition

Author: Lizabeth A. Allison
Publisher: Wiley Global Education
ISBN: 1118209885
Size: 14.79 MB
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Perfect for a single term on Molecular Biology and more accessible to beginning students in the field than its encyclopedic counterparts, Fundamental Molecular Biology provides a distillation of the essential concepts of molecular biology, and is supported by current examples, experimental evidence, an outstanding art program, multimedia support and a solid pedagogical framework. The text has been praised both for its balanced and solid coverage of traditional topics, and for its broad coverage of RNA structure and function, epigenetics and medical molecular biology.