Carbon 13 Nmr Spectroscopy Of Biological Systems

Author: Nicolau Beckmann
Publisher: Elsevier
ISBN: 0080528554
Size: 48.65 MB
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This book is intended to provide an in-depth understanding of 13C NMR as a tool in biological research. 13C NMR has provided unique information concerning complex biological systems, from proteins and nucleic acids to animals and humans. The subjects addressed include multidimensional heteronuclear techniques for structural studies of molecules in the liquid and solid states, the investigation of interactions in model membranes, the elucidation of metabolic pathwaysin vitro and in vivo on animals, and noninvasive metabolic studies performed on humans. The book is a unique mix of NMR methods and biological applications which makes it a convenient reference for those interested in research in this interdisciplinary area of physics, chemistry, biology, and medicine. An interdisciplinary text with emphasis on both 13C NMR methodology and the relevant biological and biomedical issues State-of-the-art 13C NMR techniques are described; Whenever possible, their advantages over other approaches are emphasized The chapters constitute comprehensive reviews and are written by acknowledged experts in their fields Chapters are written in a clear style, and include a large number of illustrations and comprehensive references

Encyclopedia Of Spectroscopy And Spectrometry

Author:
Publisher: Academic Press
ISBN: 0128032251
Size: 60.52 MB
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This third edition of the Encyclopedia of Spectroscopy and Spectrometry provides authoritative and comprehensive coverage of all aspects of spectroscopy and closely related subjects that use the same fundamental principles, including mass spectrometry, imaging techniques and applications. It includes the history, theoretical background, details of instrumentation and technology, and current applications of the key areas of spectroscopy. The new edition will include over 80 new articles across the field. These will complement those from the previous edition, which have been brought up-to-date to reflect the latest trends in the field. Coverage in the third edition includes: Atomic spectroscopy Electronic spectroscopy Fundamentals in spectroscopy High-Energy spectroscopy Magnetic resonance Mass spectrometry Spatially-resolved spectroscopic analysis Vibrational, rotational and Raman spectroscopies The new edition is aimed at professional scientists seeking to familiarize themselves with particular topics quickly and easily. This major reference work continues to be clear and accessible and focus on the fundamental principles, techniques and applications of spectroscopy and spectrometry. Incorporates more than 150 color figures, 5,000 references, and 300 articles for a thorough examination of the field Highlights new research and promotes innovation in applied areas ranging from food science and forensics to biomedicine and health Presents a one-stop resource for quick access to answers and an in-depth examination of topics in the spectroscopy and spectrometry arenas

Nmr In Biological Systems

Author: K.V.R. Chary
Publisher: Springer Science & Business Media
ISBN: 1402066791
Size: 56.62 MB
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During teaching NMR to students and researchers, we felt the need for a text-book which can cover modern trends in the application of NMR to biological systems. This book covers the entire area of NMR in Biological Sciences (Biomolecules, cells and tissues, animals, plants and drug design). As well as being useful to researchers, this is an excellent book for teaching a course on NMR in Biological Systems.

Nmr Spectroscopy Of Biological Solids

Author: A. Ramamoorthy
Publisher: CRC Press
ISBN: 1420027611
Size: 51.17 MB
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Over the past decade, a myriad of techniques have shown that solid-state nuclear magnetic resonance (NMR) can be used in a broad spectrum of applications with exceptionally impressive results. Solid-state NMR results can yield high-resolution details on the structure and function of many important biological solids, including viruses, fibril-forming molecules, and molecules embedded in the cell membrane. Filling a void in the current literature, NMR Spectroscopy of Biological Solids examines all the recent developments, implementation, and interpretation of solid-state NMR experiments and the advantages of applying them to biological systems. The book emphasizes how these techniques can be used to realize the structure of non-crystalline systems of any size. It explains how these isotropic and anisotropic couplings interactions are used to determine atomic-level structures of biological molecules in a non-soluble state and extrapolate the three-dimensional structure of membrane proteins using magic-angle spinning (MAS). The book also focuses on the use of multidimensional solid-state NMR methods in the study of aligned systems to provide basic information about the mechanisms of action of a variety of biologically active molecules. Addressing principles, methods, and applications, this book provides a critical selection of solid-state NMR methods for solving a wide range of practical problems that arise in both academic and industrial research of biomolecules in the solid state. NMR Spectroscopy of Biological Solids is a forward-thinking resource for students and researchers in analytical chemistry, bioengineering, material sciences, and structural genomics.

Flux Control In Biological Systems

Author: Ernst-Detlef Schulze
Publisher: Academic Press
ISBN: 0323139426
Size: 76.83 MB
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Comprehending and modelling biomass production, nutrient, and water fluxes in biological systems requires understanding control mechanisms at various levels of organiztion. This new book, with 16 pages of four-colorplates, compares patterns and mechanisms of regulation-starting from enzyme reactions and ending at the population and ecosystem level. By doing so, the book investigates the general principles of how fluxes are adjusted and regulated. Such principles areessential for preparing effective models and for predicting human impacts on ecosystems. Flux Control in Biological Systems: From Enzymes to Populations and Ecosystems will be an essential personal library addition for student and professional environmental biologists, ecologists, physiologists, biochemists, botanists, microbiologists, soil scientists, and zoologists; as well as anyone who investigate patterns of matter and energy transfer in biological systems of different levels of complexity. * Presents the mechanisms of flux control * Explains the similarities of flux control at various levels of complexity and organization * Demonstrates how fluxes are adjusted in complex systems of interacting groups of organisms

Nmr Spectroscopy Of Polymers

Author: Tatsuki Kitayama
Publisher: Springer Science & Business Media
ISBN: 9783540402206
Size: 51.16 MB
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Based on the authors ́ extensive experimental experience, NMR Spectroscopy of Polymers explains the practical use of NMR spectroscopy in polymer chemistry.

Molecular Spectroscopy Xi

Author: O. Sild
Publisher: Elsevier
ISBN: 1483284751
Size: 32.13 MB
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Molecular Spectroscopy–XI provides information pertinent to the fundamental aspects of molecular spectroscopy. This book discusses the modifications of molecular spectra when the density varies as a function of temperature and pressure. Organized into 15 chapters, this book begins with an overview of the several processes concerning triplet excitons leading to magnetic-field sensitive luminescence in organic crystals and related compounds. This text then examines the methods of investigation of the exciton band structures in molecular crystals. Other chapters consider the conditions for the equivalence of Fourier spectroscopy and of slow passage experiments in nuclear magnetic resonance. This book discusses as well the application of computer technology in carbon-13 magnetic resonance spectroscopy. The final chapter deals with the application of high-resolution proton and carbon-13 n.m.r. spectroscopy for the investigation of the molecular conformations in proteins. This book is a valuable resource for organic chemists, biologists, microbiologists, scientists, and research workers.

Structural Biology

Author: Quincy Teng
Publisher: Springer Science & Business Media
ISBN: 0387243682
Size: 39.14 MB
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Over the years since NMR was first applied to solve problems in structural biology, it has undergonedramaticdevelopmentsinbothNMRinstrumenthardwareandmethodology. While it is established that NMR is one of the most powerful tools for understanding biological p- cesses at the atomic level, it has become increasingly difficult for authors and instructors to make valid decisions concerning the content and level for a graduate course of NMR in str- turalbiology. BecausemanyofthedetailsinpracticalNMRarenotdocumentedsystematically, students entering the field have to learn the experiments and methods through communication with other experienced students or experts. Often such a learning process is incomplete and unsystematic. This book is meant to be not only a textbook, but also a handbook for those who routinely use NMR to study various biological systems. Thus, the book is organized with experimentalists in mind, whether they are instructors or students. For those who have a little or no background in NMR structural biology, it is hoped that this book will provide sufficient perspective and insight. Those who are already experienced in NMR research may find new information or different methods that are useful to their research. Because understanding fundamental principles and concepts of NMR spectroscopy is essential for the application of NMR methods to research projects, the book begins with an introduction to basic NMR principles. While detailed mathematics and quantum mechanics dealing with NMR theory have been addressed in several well-known NMR books, Chapter 1 illustrates some of the fundamental principles and concepts of NMR spectroscopy in a more descriptiveandstraightforwardmanner.