Alkaloids Chemical And Biological Perspectives

Author: S.W. Pelletier
Publisher: Elsevier
ISBN: 9780080526980
Size: 15.35 MB
Format: PDF, ePub, Docs
View: 6950
Download
Alkaloids: Chemical and Biological Perspectives, the 15th volume of the ACBP series, features four important reviews of research on alkaloids. Chapter 1 is the first comprehensive review of the carbon-13 and proton NMR shift assignments and physical constants of diterpene alkaloids and their derivatives. In addition to the catalogue of spectral and physical data, the chapter includes a table of the occurrences of these alkaloids in various plant species, tables containing molecular formulas versus calculated high-resolution mass values, and calculated high-resolution mass values versus the molecular formulas of diterpenoid alkaloids, as well as seven tables summarizing the carbon-13 chemical shifts of various functional groups in diterpenoid alkaloids. Chapter 2 is a fascinating review of the supercritical fluid extraction of alkaloids. This technique using basic modifiers, provides an alternative method for the extraction of alkaloids. Chapter 3 summarizes recent advances in the synthesis of Amaryllidaceae alkaloids, an important class of naturally-occurring bases and neutral compounds. The increased activity in the synthesis of these alkaloids over the last decade is undoubtedly due to the fact that certain members of this family possess interesting and useful biological properties. Elegant syntheses, chiral and otherwise, of structures incorporating many asymmetric centres are reviewed. Chapter 4 reviews radical cyclization reactions in the total synthesis of indole alkaloids. The use of free radical chemistry in the synthesis of alkaloids has grown markedly because of the mild reaction conditions, tolerance of a wide variety of functional groups, and the good stereoselectivities. Each chapter in this volume has been reviewed by at least one specialist in the field.

Alkaloids Chemical And Biological Perspectives

Author: S.W. Pelletier
Publisher: Elsevier
ISBN: 9780080527017
Size: 18.37 MB
Format: PDF, Kindle
View: 405
Download
Acronycine, a potent antitumor agent, was discovered in the bark of the small Australian Rutaceous tree, Acronychia baueri Schott. This new work presents a comprehensive survey of the isolation, structure determination, methods of synthesis, and the biological properties of acronycine, as well as an account of natural and synthetic analogues of acronycine, and their biological properties. Solanum alkaloids were reviewed in 1990 and this book surveys the new developments (isolation procedures, structural elucidation methods) and critically updates earlier reviews. In addition it presents the interesting chemistry and synthesis of cyclopeptide alkaloids. These cyclopeptide alkaloids have been isolated from ascidians, sea hares, and cyanobacteria. Also included are reviews of the use of the functionalized lactam, pyroglutamic acid, as a chiral template for the synthesis of alkaloids. The second review examines the on-line coupling of capillary electrophoresis (CE) and mass spectrometry (MS) for the analysis of alkaloid mixtures. Finally a review of oxygenated analogs of the alkaloid Marcfortine for their potent antiparasitic activity is included at the end of this work. Each chapter in this volume has been reviewed by at least one expert in the field. Indexes for both subjects and organisms are provided.

Alkaloids Chemical And Biological Perspectives

Author: S. William Pelletier
Publisher: Springer Science & Business Media
ISBN: 1461230063
Size: 40.66 MB
Format: PDF, Mobi
View: 1772
Download
Volume 7 of Alkaloids: Chemical and Biological Perspectives appears under the aegis of a new publisher: the distinguished firm of Springer Verlag New York, Inc. This volume presents three timely reviews on alkaloids: Chapter 1 reviews the homoerythrina and related alkaloids. a group of compounds occurring in seventeen species that are native to countries bordering the western Pacific. Since the last review in 1981, the number of these alkaloids has doubled. Chapter 2 is a comprehensive review of the carbon-13 NMR spectros copy of steroidal alkaloids. Because more than 350 plant species have yielded steroidal alkaloids and these alkaloids exhibit a wide spectrum of biological activities, including teratogenicity, this catalog of spectral and physical data should prove very useful to workers in this field. Chapter 3 presents a detailed review of proton and carbon-I3 NMR shift assignments and physical constants of norditerpenoid alkaloids. This chap ter is an extensive supplement to the review that appeared in Volume 2 of this series. In addition to the catalog of spectral and physical data, this chapter includes tables of proton and carbon shift assignments, a table of the occurrence of alkaloids in plant species, an index of al1 X-ray crystal structure determinations of norditerpenoid alkaloids, and tables containing molecular formulas versus calculated high-resolution mass values and calculated high-resolution mass values versus molecular formulas of nor diterpenoid alkaloids. Each chapter in this volume has been reviewed by an expert in the field. Indexes for both subjects and organisms are provided.

Alkaloids

Author: S. William Pelletier
Publisher: Wiley-Interscience
ISBN:
Size: 41.33 MB
Format: PDF, Mobi
View: 2808
Download

Chemistry And Biology

Author:
Publisher: Academic Press
ISBN: 9780080865744
Size: 23.39 MB
Format: PDF, ePub
View: 3627
Download
Chemistry and Biology is a celebration of the outstanding contributions to the field by Professor R.H.F. Manske, who founded the series in 1950. This special volume demonstrates the dramatic changes in alkaloidchemistry since then. It also offers a unique overview of recent developments in major areas of alkaloid chemistry and biology and looks at how these areas will develop in the future. These fourteen contributions are written by many of the leading alkaloid chemists in the world, and thus comprise a unique view of alkaloids and their contributions to the health and well-being of humankind. Indispensable reference work written by leading experts in the field Provides up-to-date, timely reviews on compounds and classes of great interest Covers synthesis, biosynthesis, biology, as well as isolation and structure elucidation An essential research tool for anyone working with alkaloids from a chemical or biological perspective

Chemistry And Pharmacology

Author:
Publisher: Academic Press
ISBN: 9780080865706
Size: 34.27 MB
Format: PDF
View: 6566
Download
Internationally acclaimed for more than forty years, this serial, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structureelucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, or various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Over the years, this series has become the standard in natural product chemistry to which all other book series aspire. The Alkaloids: Chemistry and Pharmacology endures as an essential reference for all natural product chemists and biologists who have an interest in alkaloids, their diversity, and their unique biological profile. Indispensible reference work written by leading experts in the field Provides up-to-date, timely reviews on compounds and classes of great interest Covers synthesis, biosynthesis, biology, as well as isolation and structure elucidation An essential research tool for anyone working with alkaloids from a chemical or biological perspective

Alkaloids

Author: S. William Pelletier
Publisher: Wiley-Interscience
ISBN:
Size: 20.36 MB
Format: PDF, ePub
View: 701
Download
For centuries, human inhabitants of Central and South America have poisoned blow darts with alkaloids they extract from the brightly coloured frogs of the rain forests. Volume 4 of

Alkaloids Secrets Of Life

Author: Tadeusz Aniszewski
Publisher: Elsevier
ISBN: 9780080475332
Size: 43.69 MB
Format: PDF, Mobi
View: 4070
Download
Alkaloids, represent a group of interesting and complex chemical compounds, produced by the secondary metabolism of living organisms in different biotopes. They are relatively common chemicals in all kingdoms of living organisms in all environments. Two hundred years of scientific research has still not fully explained the connections between alkaloids and life. Alkaloids-Chemistry, Biological Significance, Applications and Ecological Role provides knowledge on structural typology, biosynthesis and metabolism in relation to recent research work on alkaloids. Considering an organic chemistry approach to alkaloids using biological and ecological explanation. Within the book several questions that persist in this field of research are approached as are some unresearched areas. The book provides beneficial text for an academic and professional audience and serves as a source of knowledge for anyone who is interested in the fascinating subject of alkaloids. Each chapter features an abstract. Appendices are included, as are a listing of alkaloids, plants containing alkaloids and some basic protocols of alkaloid analysis. * Presents the ecological role of alkaloids in nature and ecosystems * Interdisciplinary and reader friendly approach * Up-to-date knowledge

R Mpp Encyclopedia Natural Products 1st Edition 2000

Author: Burkhard Fugmann
Publisher: Georg Thieme Verlag
ISBN: 3131795514
Size: 16.67 MB
Format: PDF, Docs
View: 6269
Download
Compiled by German natural products chemist Wolfgang Steglich and his co-editors Burkhard Fugmann and Susanne Lang-Fugmann, RÖMPP Encyclopedia Natural Products provides highly reliable and comprehensive information on the 6,000 most relevant natural substances, including 15,000 cross references and 2,200 formulas. The book contains descriptions of the different substance classes and important analytical methods, comprehensive indices of Latin Species names and molecular formulas as well as a vast amount of cross referencing. It has been compiled by 40 leaders in their respective fields. Written in a clear, consistent style and thoroughly copy edited, this is a must-have reference work for chemists, biochemists working with natural products, researchers in plant protection, pharmacists and medical researchers, biologists working in drug research as well as microbiologists and botanists working on microorganisms, plants or marine organisms, and interested layman.

Synthesis Of Medicinal Agents From Plants

Author: Ashish Tewari
Publisher: Elsevier
ISBN: 0081022743
Size: 32.48 MB
Format: PDF, ePub, Docs
View: 842
Download
Synthesis of Medicinal Agents from Plants highlights the importance of synthesizing medicinal agents from plants and outlines methods for performing it effectively. Beginning with an introduction to the significance of medicinal plants, the book goes on to provide a historical overview of drug synthesis before exploring how this can be used to successfully replicate and adapt the active agents from natural sources. Chapters then explore the medicinal properties of a number of important plants, before concluding with a discussion of the future of drugs from medicinal plants. Illustrated with real-world examples, it is a practical resource for researchers in this field. In an age of rapid environmental destruction, hundreds of medicinal plants are at risk of extinction from overexploitation and deforestation, limiting the natural resources available for active agent extraction, thereby threatening the discovery of future cures for diseases. Simultaneously, with the increasing population and advances in medical sciences, the demand for drugs is continuously increasing and cannot be met with just plants. The ability to synthetically replicate the active compounds from these plants is essential in creating an ecologically-aware, sustainable future for drug design Includes detailed coverage of therapeutic compound synthesis Uses multiple real-world examples to support content Lays out a sustainable template for the future of developing active agents from natural products